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YEAST:URE2
Contents
| Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
| Gene Name(s) | URE2 | |
| Protein Name(s) | Transcriptional regulator URE2
Disulfide reductase Glutathione peroxidase | |
| External Links | ||
| UniProt | P23202 | |
| EMBL | M35268 AF525174 AF525175 AF525176 AF525177 AF525178 AF525179 AF525180 AF525181 AF525182 AF525183 AF525184 AF525185 AF525186 AF525187 AF525188 AF525189 AF525190 AF525191 AF525192 Z69381 Z71505 BK006947 | |
| PIR | A39609 | |
| RefSeq | NP_014170.1 | |
| PDB | 1G6W 1G6Y 1HQO 1JZR 1K0A 1K0B 1K0C 1K0D | |
| PDBsum | 1G6W 1G6Y 1HQO 1JZR 1K0A 1K0B 1K0C 1K0D | |
| DisProt | DP00353 | |
| ProteinModelPortal | P23202 | |
| SMR | P23202 | |
| BioGrid | 35609 | |
| DIP | DIP-1308N | |
| IntAct | P23202 | |
| MINT | MINT-393865 | |
| STRING | 4932.YNL229C | |
| MaxQB | P23202 | |
| PaxDb | P23202 | |
| PeptideAtlas | P23202 | |
| EnsemblFungi | [example_ID YNL229C] | |
| GeneID | 855492 | |
| KEGG | sce:YNL229C | |
| CYGD | YNL229c | |
| SGD | S000005173 | |
| eggNOG | COG0625 | |
| HOGENOM | HOG000125742 | |
| InParanoid | P23202 | |
| KO | K00799 | |
| OMA | VYKWTKH | |
| OrthoDB | EOG7KWSWX | |
| BioCyc | YEAST:YNL229C-MONOMER | |
| EvolutionaryTrace | P23202 | |
| NextBio | 979478 | |
| Proteomes | UP000002311 | |
| ExpressionAtlas | P23202 | |
| Genevestigator | P23202 | |
| GO | GO:0005829 GO:0004602 GO:0051219 GO:0003714 GO:0051220 GO:0042994 GO:1903507 GO:0042128 GO:0032447 GO:0006808 GO:0010044 | |
| Gene3D | 1.20.1050.10 3.40.30.10 | |
| InterPro | IPR010987 IPR004045 IPR004046 IPR012336 IPR017298 | |
| Pfam | PF00043 PF02798 | |
| PIRSF | PIRSF037861 | |
| SUPFAM | SSF47616 SSF52833 | |
| PROSITE | PS50405 PS50404 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0042994 |
cytoplasmic sequestering of transcription factor |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
has_input:(UniProtKB:P43574) |
Seeded From UniProt |
complete | ||
|
enables |
GO:0051219 |
phosphoprotein binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042994 |
cytoplasmic sequestering of transcription factor |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
has_input:(UniProtKB:P18494) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0032447 |
protein urmylation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0010044 |
response to aluminum ion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006808 |
regulation of nitrogen utilization |
ECO:0000353 |
physical interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006808 |
regulation of nitrogen utilization |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006808 |
regulation of nitrogen utilization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004602 |
glutathione peroxidase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0098869 |
cellular oxidant detoxification |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0004602 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0098869 |
cellular oxidant detoxification |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004602 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:1903507 |
negative regulation of nucleic acid-templated transcription |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0003714 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003714 |
transcription corepressor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006808 |
regulation of nitrogen utilization |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004602 |
glutathione peroxidase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042128 |
nitrate assimilation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Cunningham, TS et al. (2000) Nitrogen catabolite repression of DAL80 expression depends on the relative levels of Gat1p and Ure2p production in Saccharomyces cerevisiae. J. Biol. Chem. 275 14408-14 PubMed GONUTS page
- ↑ Beck, T & Hall, MN (1999) The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors. Nature 402 689-92 PubMed GONUTS page
- ↑ 3.0 3.1 Cox, KH et al. (2000) Saccharomyces cerevisiae GATA sequences function as TATA elements during nitrogen catabolite repression and when Gln3p is excluded from the nucleus by overproduction of Ure2p. J. Biol. Chem. 275 17611-8 PubMed GONUTS page
- ↑ Goehring, AS et al. (2003) Urmylation: a ubiquitin-like pathway that functions during invasive growth and budding in yeast. Mol. Biol. Cell 14 4329-41 PubMed GONUTS page
- ↑ Basu, U et al. (2004) Reverse genetic analysis of the glutathione metabolic pathway suggests a novel role of PHGPX and URE2 genes in aluminum resistance in Saccharomyces cerevisiae. Mol. Genet. Genomics 271 627-37 PubMed GONUTS page
- ↑ 6.0 6.1 Blinder, D et al. (1996) Interaction of the GATA factor Gln3p with the nitrogen regulator Ure2p in Saccharomyces cerevisiae. J. Bacteriol. 178 4734-6 PubMed GONUTS page
- ↑ Coffman, JA et al. (1994) The URE2 protein regulates nitrogen catabolic gene expression through the GATAA-containing UASNTR element in Saccharomyces cerevisiae. J. Bacteriol. 176 7476-83 PubMed GONUTS page
- ↑ Bai, M et al. (2004) The yeast prion protein Ure2 shows glutathione peroxidase activity in both native and fibrillar forms. J. Biol. Chem. 279 50025-30 PubMed GONUTS page
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