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YEAST:TIM22
Contents
| Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
| Gene Name(s) | TIM22 | |
| Protein Name(s) | Mitochondrial import inner membrane translocase subunit TIM22 | |
| External Links | ||
| UniProt | Q12328 | |
| EMBL | X99000 Z74265 AY558171 BK006938 | |
| PIR | S67776 | |
| RefSeq | NP_010064.1 | |
| ProteinModelPortal | Q12328 | |
| BioGrid | 31828 | |
| DIP | DIP-1142N | |
| IntAct | Q12328 | |
| MINT | MINT-513851 | |
| TCDB | 3.A.8.1.1 | |
| MaxQB | Q12328 | |
| EnsemblFungi | YDL217C | |
| GeneID | 851309 | |
| KEGG | sce:YDL217C | |
| EuPathDB | FungiDB:YDL217C | |
| SGD | S000002376 | |
| GeneTree | ENSGT00390000016067 | |
| HOGENOM | HOG000161169 | |
| InParanoid | Q12328 | |
| KO | K17790 | |
| OMA | NFGYIGM | |
| OrthoDB | EOG7F7WN2 | |
| BioCyc | YEAST:G3O-29598-MONOMER | |
| Reactome | [www.reactome.org/content/detail/R-SCE-1268020 R-SCE-1268020] | |
| PRO | PR:Q12328 | |
| Proteomes | UP000002311 | |
| GO | GO:0005829 GO:0016021 GO:0005743 GO:0042721 GO:0005758 GO:0030943 GO:0015266 GO:0045039 GO:0006626 | |
| InterPro | IPR003397 | |
| Pfam | PF02466 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045039 |
protein insertion into mitochondrial inner membrane |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045039 |
protein insertion into mitochondrial inner membrane |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042721 |
TIM22 mitochondrial import inner membrane insertion complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042721 |
TIM22 mitochondrial import inner membrane insertion complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0030943 |
mitochondrion targeting sequence binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008320 |
protein transmembrane transporter activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045039 |
protein insertion into mitochondrial inner membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000364156 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0042721 |
TIM22 mitochondrial import inner membrane insertion complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000364156 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0030943 |
mitochondrion targeting sequence binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000364156 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008320 |
protein transmembrane transporter activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000364156 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0071806 |
protein transmembrane transport |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0008320 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0071806 |
protein transmembrane transport |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0008320 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0042721 |
TIM22 mitochondrial import inner membrane insertion complex |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045039 |
protein insertion into mitochondrial inner membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
Reactome:R-SCE-1252255 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005758 |
mitochondrial intermembrane space |
Reactome:R-SCE-1252259 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
|
part_of |
GO:0005743 |
mitochondrial inner membrane |
Reactome:R-SCE-1252258 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0015031 |
protein transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005743 |
mitochondrial inner membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Reinders, J et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J. Proteome Res. 5 1543-54 PubMed GONUTS page
- ↑ Renvoisé, M et al. (2014) Quantitative variations of the mitochondrial proteome and phosphoproteome during fermentative and respiratory growth in Saccharomyces cerevisiae. J Proteomics 106 140-50 PubMed GONUTS page
- ↑ 3.0 3.1 Koehler, CM et al. (2000) Tim18p, a new subunit of the TIM22 complex that mediates insertion of imported proteins into the yeast mitochondrial inner membrane. Mol. Cell. Biol. 20 1187-93 PubMed GONUTS page
- ↑ Sirrenberg, C et al. (1996) Import of carrier proteins into the mitochondrial inner membrane mediated by Tim22. Nature 384 582-5 PubMed GONUTS page
- ↑ Kerscher, O et al. (2000) Tim18p is a new component of the Tim54p-Tim22p translocon in the mitochondrial inner membrane. Mol. Biol. Cell 11 103-16 PubMed GONUTS page
- ↑ 6.0 6.1 Kovermann, P et al. (2002) Tim22, the essential core of the mitochondrial protein insertion complex, forms a voltage-activated and signal-gated channel. Mol. Cell 9 363-73 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 7.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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