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YEAST:STE2
Contents
| Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
| Gene Name(s) | STE2 | |
| Protein Name(s) | Pheromone alpha factor receptor | |
| External Links | ||
| UniProt | D6VTK4 | |
| EMBL | X03010 M24335 AJ585736 D50617 AY693134 BK006940 | |
| PIR | S56228 | |
| RefSeq | NP_116627.2 | |
| PDB | 1PJD 2K9P | |
| PDBsum | 1PJD 2K9P | |
| ProteinModelPortal | D6VTK4 | |
| SMR | D6VTK4 | |
| BioGrid | 31120 | |
| IntAct | D6VTK4 | |
| MaxQB | D6VTK4 | |
| EnsemblFungi | [example_ID YFL026W] | |
| GeneID | 850518 | |
| KEGG | sce:YFL026W | |
| SGD | S000001868 | |
| InParanoid | D6VTK4 | |
| KO | K11213 | |
| OMA | FHILLIM | |
| OrthoDB | EOG7QVMD0 | |
| BioCyc | YEAST:G3O-30434-MONOMER | |
| EvolutionaryTrace | D6VTK4 | |
| NextBio | 966245 | |
| Proteomes | UP000002311 | |
| ExpressionAtlas | D6VTK4 | |
| GO | GO:0005887 GO:0004934 GO:0030031 GO:0000755 GO:0000750 GO:0051260 | |
| Gene3D | 1.10.287.920 | |
| InterPro | IPR000366 IPR027458 | |
| Pfam | PF02116 | |
| PRINTS | PR00250 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0051260 |
protein homooligomerization |
ECO:0000353 |
physical interaction evidence used in manual assertion |
SGD:S000001868 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030031 |
cell projection assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004934 |
mating-type alpha-factor pheromone receptor activity |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
SGD:S000001047 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004934 |
mating-type alpha-factor pheromone receptor activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004934 |
mating-type alpha-factor pheromone receptor activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004934 |
mating-type alpha-factor pheromone receptor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004934 |
mating-type alpha-factor pheromone receptor activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
Missing: with/from | |||
|
involved_in |
GO:0000755 |
cytogamy |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0000755 |
cytogamy |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0000750 |
pheromone-dependent signal transduction involved in conjugation with cellular fusion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0038038 |
G protein-coupled receptor homodimeric complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001997318 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0035624 |
receptor transactivation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001997318 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0031139 |
positive regulation of conjugation with cellular fusion |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001997318 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005550 |
pheromone binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001997318 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0000750 |
pheromone-dependent signal transduction involved in conjugation with cellular fusion |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001997318 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004932 |
mating-type factor pheromone receptor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007186 |
G protein-coupled receptor signaling pathway |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019236 |
response to pheromone |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007186 |
G protein-coupled receptor signaling pathway |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007165 |
signal transduction |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004930 |
G protein-coupled receptor activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Gehret, AU et al. (2006) Oligomerization of the yeast alpha-factor receptor: implications for dominant negative effects of mutant receptors. J. Biol. Chem. 281 20698-714 PubMed GONUTS page
- ↑ Vallier, LG et al. (2002) The alpha-factor receptor C-terminus is important for mating projection formation and orientation in Saccharomyces cerevisiae. Cell Motil. Cytoskeleton 53 251-66 PubMed GONUTS page
- ↑ Blumer, KJ et al. (1988) The STE2 gene product is the ligand-binding component of the alpha-factor receptor of Saccharomyces cerevisiae. J. Biol. Chem. 263 10836-42 PubMed GONUTS page
- ↑ 4.0 4.1 Dosil, M et al. (1998) Dominant-negative mutations in the G-protein-coupled alpha-factor receptor map to the extracellular ends of the transmembrane segments. Mol. Cell. Biol. 18 5981-91 PubMed GONUTS page
- ↑ Jenness, DD et al. (1983) Binding of alpha-factor pheromone to yeast a cells: chemical and genetic evidence for an alpha-factor receptor. Cell 35 521-9 PubMed GONUTS page
- ↑ Blumer, KJ & Thorner, J (1990) Beta and gamma subunits of a yeast guanine nucleotide-binding protein are not essential for membrane association of the alpha subunit but are required for receptor coupling. Proc. Natl. Acad. Sci. U.S.A. 87 4363-7 PubMed GONUTS page
- ↑ Burkholder, AC & Hartwell, LH (1985) The yeast alpha-factor receptor: structural properties deduced from the sequence of the STE2 gene. Nucleic Acids Res. 13 8463-75 PubMed GONUTS page
- ↑ 8.0 8.1 Shi, C et al. (2007) A role for a complex between activated G protein-coupled receptors in yeast cellular mating. Proc. Natl. Acad. Sci. U.S.A. 104 5395-400 PubMed GONUTS page
- ↑ Jenness, DD et al. (1987) Saccharomyces cerevisiae mutants unresponsive to alpha-factor pheromone: alpha-factor binding and extragenic suppression. Mol. Cell. Biol. 7 1311-9 PubMed GONUTS page
- ↑ 10.0 10.1 10.2 10.3 10.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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