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YEAST:SET3

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Species (Taxon ID) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292)
Gene Name(s) SET3
Protein Name(s) SET domain-containing protein 3
External Links
UniProt P36124
EMBL Z28254
BK006944
PIR S38101
RefSeq NP_012954.3
ProteinModelPortal P36124
SMR P36124
BioGrid 34162
DIP DIP-5632N
IntAct P36124
MINT MINT-548373
MaxQB P36124
PaxDb P36124
EnsemblFungi [example_ID YKR029C]
GeneID 853900
KEGG sce:YKR029C
CYGD YKR029c
EuPathDB FungiDB:YKR029C
SGD S000001737
eggNOG COG2940
GeneTree ENSGT00700000105281
HOGENOM HOG000141785
InParanoid P36124
KO K07117
OMA FTIQCDH
OrthoDB EOG793BH2
BioCyc YEAST:G3O-32005-MONOMER
NextBio 975224
PRO PR:P36124
Proteomes UP000002311
GO GO:0034967
GO:0035064
GO:0008270
GO:0016575
GO:0051321
GO:0045835
GO:0006355
GO:0006351
Gene3D 3.30.40.10
InterPro IPR001214
IPR019786
IPR011011
IPR001965
IPR019787
IPR013083
Pfam PF00628
SMART SM00249
SM00317
SUPFAM SSF57903
PROSITE PS50280
PS01359
PS50016

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0035961

positive regulation of ergosterol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter

PMID:23382196[1]

ECO:0000315

P

Figure 6

complete
CACAO 11010

GO:0070452

positive regulation of ergosterol biosynthetic process

PMID:23382196[1]

ECO:0000315

P

Figure 6

complete
CACAO 11055

enables

GO:0035064

methylated histone binding

PMID:23798402[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0070210

Rpd3L-Expanded complex

PMID:19040720[3]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0045835

negative regulation of meiotic nuclear division

PMID:11711434[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0035064

methylated histone binding

PMID:17142463[5]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0034967

Set3 complex

PMID:11711434[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0016575

histone deacetylation

PMID:11711434[4]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

PMID:19379692[6]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0006325

chromatin organization

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0156

P

Seeded From UniProt

complete

involved_in

GO:0051321

meiotic cell cycle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0469

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 South, PF et al. (2013) H3K4 methyltransferase Set1 is involved in maintenance of ergosterol homeostasis and resistance to Brefeldin A. Proc. Natl. Acad. Sci. U.S.A. 110 E1016-25 PubMed GONUTS page
  2. Ali, M et al. (2013) Molecular basis for chromatin binding and regulation of MLL5. Proc. Natl. Acad. Sci. U.S.A. 110 11296-301 PubMed GONUTS page
  3. Shevchenko, A et al. (2008) Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment. Genome Biol. 9 R167 PubMed GONUTS page
  4. 4.0 4.1 4.2 Pijnappel, WW et al. (2001) The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program. Genes Dev. 15 2991-3004 PubMed GONUTS page
  5. Shi, X et al. (2007) Proteome-wide analysis in Saccharomyces cerevisiae identifies several PHD fingers as novel direct and selective binding modules of histone H3 methylated at either lysine 4 or lysine 36. J. Biol. Chem. 282 2450-5 PubMed GONUTS page
  6. Kim, T & Buratowski, S (2009) Dimethylation of H3K4 by Set1 recruits the Set3 histone deacetylase complex to 5' transcribed regions. Cell 137 259-72 PubMed GONUTS page