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YEAST:PEX3

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Species (Taxon ID) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292)
Gene Name(s) PEX3 (synonyms: PAS3)
Protein Name(s) Peroxisomal biogenesis factor 3

Peroxin-3 Peroxisomal membrane protein PAS3

External Links
UniProt P28795
EMBL X58407
U32517
BK006938
PIR A40550
RefSeq NP_010616.3
ProteinModelPortal P28795
BioGrid 32386
DIP DIP-2477N
IntAct P28795
MINT MINT-474353
STRING 4932.YDR329C
TCDB 3.A.20.1.5
9.A.17.1.1
MaxQB P28795
PaxDb P28795
EnsemblFungi [example_ID YDR329C]
GeneID 851929
KEGG sce:YDR329C
CYGD YDR329c
SGD S000002737
eggNOG NOG302392
HOGENOM HOG000001061
InParanoid P28795
KO K13336
OMA INEQAFL
OrthoDB EOG7RJQ17
BioCyc YEAST:G3O-29885-MONOMER
NextBio 969986
Proteomes UP000002311
Genevestigator P28795
GO GO:0005783
GO:0005779
GO:0005778
GO:0005777
GO:0030674
GO:0032581
GO:0045033
GO:0045046
InterPro IPR006966
Pfam PF04882

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0045046

protein import into peroxisome membrane

PMID:10637226[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045033

peroxisome inheritance

PMID:19948495[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0032581

ER-dependent peroxisome organization

PMID:20427571[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0032581

ER-dependent peroxisome organization

PMID:17646399[4]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0030674

protein binding, bridging

PMID:23900285[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

PMID:16009135[6]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005778

peroxisomal membrane

PMID:1894692[7]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005777

peroxisome

PMID:23900285[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0045046

protein import into peroxisome membrane

PMID:21873635[8]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001489815
SGD:S000002737
UniProtKB:P56589

P

Seeded From UniProt

complete

enables

GO:0030674

protein binding, bridging

PMID:21873635[8]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001489815
SGD:S000002737

F

Seeded From UniProt

complete

part_of

GO:0005779

integral component of peroxisomal membrane

PMID:21873635[8]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001489815
UniProtKB:P56589

C

Seeded From UniProt

complete

part_of

GO:0005779

integral component of peroxisomal membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006966

C

Seeded From UniProt

complete

involved_in

GO:0007031

peroxisome organization

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006966

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0005777

peroxisome

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0576

C

Seeded From UniProt

complete

part_of

GO:0005778

peroxisomal membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0203

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Hettema, EH et al. (2000) Saccharomyces cerevisiae pex3p and pex19p are required for proper localization and stability of peroxisomal membrane proteins. EMBO J. 19 223-33 PubMed GONUTS page
  2. Munck, JM et al. (2009) A dual function for Pex3p in peroxisome formation and inheritance. J. Cell Biol. 187 463-71 PubMed GONUTS page
  3. van der Zand, A et al. (2010) Peroxisomal membrane proteins insert into the endoplasmic reticulum. Mol. Biol. Cell 21 2057-65 PubMed GONUTS page
  4. Motley, AM & Hettema, EH (2007) Yeast peroxisomes multiply by growth and division. J. Cell Biol. 178 399-410 PubMed GONUTS page
  5. 5.0 5.1 Knoblach, B et al. (2013) An ER-peroxisome tether exerts peroxisome population control in yeast. EMBO J. 32 2439-53 PubMed GONUTS page
  6. Hoepfner, D et al. (2005) Contribution of the endoplasmic reticulum to peroxisome formation. Cell 122 85-95 PubMed GONUTS page
  7. Höhfeld, J et al. (1991) PAS3, a Saccharomyces cerevisiae gene encoding a peroxisomal integral membrane protein essential for peroxisome biogenesis. J. Cell Biol. 114 1167-78 PubMed GONUTS page
  8. 8.0 8.1 8.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page