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YEAST:MYO5
Contents
| Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
| Gene Name(s) | MYO5 | |
| Protein Name(s) | Myosin-5
Actin-dependent myosin-I MYO5 Class I unconventional myosin MYO5 Type I myosin MYO5 | |
| External Links | ||
| UniProt | Q04439 | |
| EMBL | Z49702 BK006946 | |
| PIR | S54570 | |
| RefSeq | NP_013827.1 | |
| PDB | 1YP5 1ZUY | |
| PDBsum | 1YP5 1ZUY | |
| ProteinModelPortal | Q04439 | |
| SMR | Q04439 | |
| BioGrid | 35285 | |
| DIP | DIP-2222N | |
| IntAct | Q04439 | |
| MINT | MINT-593586 | |
| STRING | 4932.YMR109W | |
| MaxQB | Q04439 | |
| PaxDb | Q04439 | |
| PeptideAtlas | Q04439 | |
| EnsemblFungi | [example_ID YMR109W] | |
| GeneID | 855136 | |
| KEGG | sce:YMR109W | |
| CYGD | YMR109w | |
| SGD | S000004715 | |
| eggNOG | COG5022 | |
| GeneTree | ENSGT00760000118956 | |
| HOGENOM | HOG000260265 | |
| InParanoid | Q04439 | |
| KO | K10356 | |
| OMA | HVILESN | |
| OrthoDB | EOG7VDXXK | |
| BioCyc | YEAST:G3O-32805-MONOMER | |
| EvolutionaryTrace | Q04439 | |
| NextBio | 978516 | |
| Proteomes | UP000002311 | |
| Genevestigator | Q04439 | |
| GO | GO:0030479 GO:0016459 GO:0005524 GO:0042802 GO:0000146 GO:0051666 GO:0007121 GO:0006897 GO:0006887 GO:0031505 GO:0008152 GO:0006898 GO:0006970 GO:0009651 | |
| InterPro | IPR001609 IPR010926 IPR027417 IPR001452 | |
| Pfam | PF00063 PF06017 PF00018 | |
| PRINTS | PR00193 | |
| SMART | SM00242 SM00326 | |
| SUPFAM | SSF50044 SSF52540 | |
| PROSITE | PS51456 PS50002 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0005933 |
cellular bud |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0071944 |
cell periphery |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0043332 |
mating projection tip |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:2000601 |
positive regulation of Arp2/3 complex-mediated actin nucleation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:2000601 |
positive regulation of Arp2/3 complex-mediated actin nucleation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0051666 |
actin cortical patch localization |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
SGD:S000001612 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0051666 |
actin cortical patch localization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030479 |
actin cortical patch |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030479 |
actin cortical patch |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009651 |
response to salt stress |
ECO:0000353 |
physical interaction evidence used in manual assertion |
SGD:S000001156 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0009651 |
response to salt stress |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
SGD:S000001156 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006898 |
receptor-mediated endocytosis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006897 |
endocytosis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000146 |
microfilament motor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003774 |
motor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016459 |
myosin complex |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0031505 |
fungal-type cell wall organization |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007121 |
bipolar cellular bud site selection |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006970 |
response to osmotic stress |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006887 |
exocytosis |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003779 |
actin binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005856 |
cytoskeleton |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016459 |
myosin complex |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030479 |
actin cortical patch |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Yofe, I et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat. Methods 13 371-378 PubMed GONUTS page
- ↑ Narayanaswamy, R et al. (2009) Systematic definition of protein constituents along the major polarization axis reveals an adaptive reuse of the polarization machinery in pheromone-treated budding yeast. J. Proteome Res. 8 6-19 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 Sun, Y et al. (2006) Endocytic internalization in budding yeast requires coordinated actin nucleation and myosin motor activity. Dev. Cell 11 33-46 PubMed GONUTS page
- ↑ 4.0 4.1 Galletta, BJ et al. (2008) Distinct roles for Arp2/3 regulators in actin assembly and endocytosis. PLoS Biol. 6 e1 PubMed GONUTS page
- ↑ 5.0 5.1 Grötsch, H et al. (2010) Calmodulin dissociation regulates Myo5 recruitment and function at endocytic sites. EMBO J. 29 2899-914 PubMed GONUTS page
- ↑ 6.0 6.1 Soulard, A et al. (2002) Saccharomyces cerevisiae Bzz1p is implicated with type I myosins in actin patch polarization and is able to recruit actin-polymerizing machinery in vitro. Mol. Cell. Biol. 22 7889-906 PubMed GONUTS page
- ↑ Geli, MI & Riezman, H (1996) Role of type I myosins in receptor-mediated endocytosis in yeast. Science 272 533-5 PubMed GONUTS page
- ↑ Anderson, BL et al. (1998) The Src homology domain 3 (SH3) of a yeast type I myosin, Myo5p, binds to verprolin and is required for targeting to sites of actin polarization. J. Cell Biol. 141 1357-70 PubMed GONUTS page
- ↑ Tonikian, R et al. (2009) Bayesian modeling of the yeast SH3 domain interactome predicts spatiotemporal dynamics of endocytosis proteins. PLoS Biol. 7 e1000218 PubMed GONUTS page
- ↑ Tarassov, K et al. (2008) An in vivo map of the yeast protein interactome. Science 320 1465-70 PubMed GONUTS page
- ↑ Tong, AH et al. (2002) A combined experimental and computational strategy to define protein interaction networks for peptide recognition modules. Science 295 321-4 PubMed GONUTS page
- ↑ 12.0 12.1 12.2 12.3 Pruyne, D & Bretscher, A (2000) Polarization of cell growth in yeast. J. Cell. Sci. 113 ( Pt 4) 571-85 PubMed GONUTS page
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