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YEAST:MTCU1
Contents
| Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
| Gene Name(s) | CUP1-1 (synonyms: MTH1) | |
| Protein Name(s) | Copper metallothionein 1-1
Cu-MT Cu-metallothionein Copper chelatin Copper thionein | |
| External Links | ||
| UniProt | P0CX80 | |
| EMBL | K02204 U00061 AY558517 BK006934 | |
| PIR | S14049 | |
| RefSeq | NP_011920.1 NP_011922.1 | |
| PDB | 1AOO 1AQQ 1AQR 1AQS 1FMY 1RJU | |
| PDBsum | 1AOO 1AQQ 1AQR 1AQS 1FMY 1RJU | |
| ProteinModelPortal | P0CX80 | |
| SMR | P0CX80 | |
| BioGrid | 36485 36487 | |
| MINT | MINT-555823 | |
| MaxQB | P0CX80 | |
| EnsemblFungi | [example_ID YHR053C] [example_ID YHR055C] | |
| GeneID | 856450 856452 | |
| KEGG | sce:YHR053C sce:YHR055C | |
| CYGD | YHR053c | |
| SGD | S000001095 | |
| OrthoDB | EOG71RXZ7 | |
| BioCyc | YEAST:G3O-31107-MONOMER | |
| EvolutionaryTrace | P0CX80 | |
| NextBio | 982075 | |
| Proteomes | UP000002311 | |
| GO | GO:0005829 GO:0016209 GO:0046870 GO:0005507 GO:0004784 GO:0071585 GO:0010273 GO:0019430 GO:0046688 | |
| Gene3D | 4.10.650.10 | |
| InterPro | IPR017854 IPR022710 | |
| Pfam | PF11403 | |
| SUPFAM | SSF57868 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0046872 |
metal ion binding |
ECO:0000314 |
F |
This paper tests the effects of Copper metallothionein 1-1 and discusses its use in metal ion binding. With this, Figures 1-5 display necessary information for this annotation that describes how the copper-metallothionein helps protect against copper toxicity. |
complete | |||||
|
part_of |
GO:0005829 |
cytosol |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0071585 |
detoxification of cadmium ion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046870 |
cadmium ion binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046688 |
response to copper ion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019430 |
removal of superoxide radicals |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
SGD:S000003865 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0019430 |
removal of superoxide radicals |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016209 |
antioxidant activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0010273 |
detoxification of copper ion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005507 |
copper ion binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004784 |
superoxide dismutase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005507 |
copper ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0010273 |
detoxification of copper ion |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046870 |
cadmium ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0071585 |
detoxification of cadmium ion |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Schwartz, JA et al. (2013) Regulation of copper toxicity by Candida albicans GPA2. Eukaryotic Cell 12 954-61 PubMed GONUTS page
- ↑ Yofe, I et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat. Methods 13 371-378 PubMed GONUTS page
- ↑ 3.0 3.1 Ecker, DJ et al. (1986) Yeast metallothionein function in metal ion detoxification. J. Biol. Chem. 261 16895-900 PubMed GONUTS page
- ↑ 4.0 4.1 Winge, DR et al. (1985) Yeast metallothionein. Sequence and metal-binding properties. J. Biol. Chem. 260 14464-70 PubMed GONUTS page
- ↑ Butt, TR et al. (1984) Cloning and expression of a yeast copper metallothionein gene. Gene 27 23-33 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 Tamai, KT et al. (1993) Yeast and mammalian metallothioneins functionally substitute for yeast copper-zinc superoxide dismutase. Proc. Natl. Acad. Sci. U.S.A. 90 8013-7 PubMed GONUTS page
- ↑ Wright, CF et al. (1987) Structural and functional studies of the amino terminus of yeast metallothionein. J. Biol. Chem. 262 12912-9 PubMed GONUTS page
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