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YEAST:MET16
Contents
| Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
| Gene Name(s) | MET16 | |
| Protein Name(s) | Phosphoadenosine phosphosulfate reductase
3'-phosphoadenylylsulfate reductase PAPS reductase, thioredoxin dependent PAdoPS reductase | |
| External Links | ||
| UniProt | P18408 | |
| EMBL | J05591 U25840 AY693236 BK006949 | |
| PIR | S59826 | |
| RefSeq | NP_015493.1 | |
| PDB | 2OQ2 | |
| PDBsum | 2OQ2 | |
| ProteinModelPortal | P18408 | |
| SMR | P18408 | |
| BioGrid | 36340 | |
| DIP | DIP-6611N | |
| MINT | MINT-677033 | |
| STRING | 4932.YPR167C | |
| MaxQB | P18408 | |
| PaxDb | P18408 | |
| PeptideAtlas | P18408 | |
| EnsemblFungi | [example_ID YPR167C] | |
| GeneID | 856296 | |
| KEGG | sce:YPR167C | |
| CYGD | YPR167c | |
| SGD | S000006371 | |
| eggNOG | COG0175 | |
| HOGENOM | HOG000249397 | |
| InParanoid | P18408 | |
| KO | K00390 | |
| OMA | PRNKLLD | |
| OrthoDB | EOG7P2Z3B | |
| BioCyc | MetaCyc:MONOMER-384 YEAST:YPR167C-MONOMER | |
| UniPathway | UPA00140 | |
| EvolutionaryTrace | P18408 | |
| NextBio | 981647 | |
| PRO | PR:P18408 | |
| Proteomes | UP000002311 | |
| Genevestigator | P18408 | |
| GO | GO:0005737 GO:0004604 GO:0019344 GO:0070814 GO:0009086 GO:0019379 GO:0000096 | |
| Gene3D | 3.40.50.620 | |
| InterPro | IPR004511 IPR002500 IPR011800 IPR014729 | |
| Pfam | PF01507 | |
| PIRSF | PIRSF000857 | |
| TIGRFAMs | TIGR00434 TIGR02057 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0006750 |
glutathione biosynthetic process |
ECO:0000315 |
P |
Fig 2 shows MET16 strain has higher level of glutathione produced. |
complete | |||||
|
involved_in |
GO:0006750 |
glutathione biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019379 |
sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019379 |
sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000305 |
curator inference used in manual assertion |
GO:0004604 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004604 |
phosphoadenylyl-sulfate reductase (thioredoxin) activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004604 |
phosphoadenylyl-sulfate reductase (thioredoxin) activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019379 |
sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10189 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004604 |
phosphoadenylyl-sulfate reductase (thioredoxin) activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10189 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003824 |
catalytic activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004604 |
phosphoadenylyl-sulfate reductase (thioredoxin) activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019379 |
sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004604 |
phosphoadenylyl-sulfate reductase (thioredoxin) activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0098624 |
3'-Phosphoadenylylselenate reductase activity |
Reactome:R-SCE-2408518 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
Reactome:R-SCE-2408518 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0008652 |
cellular amino acid biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009086 |
methionine biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019344 |
cysteine biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0070814 |
hydrogen sulfide biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00140 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Hara, KY et al. (2012) Improvement of glutathione production by metabolic engineering the sulfate assimilation pathway of Saccharomyces cerevisiae. Appl. Microbiol. Biotechnol. 94 1313-9 PubMed GONUTS page
- ↑ Masselot, M & Surdin-Kerjan, Y (1977) Methionine biosynthesis in Saccharomyces cerevisiae. II. Gene-enzyme relationships in the sulfate assimilation pathway. Mol. Gen. Genet. 154 23-30 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Schwenn, JD et al. (1988) Yeast PAPS reductase: properties and requirements of the purified enzyme. Arch. Microbiol. 150 313-9 PubMed GONUTS page
- ↑ Thomas, D et al. (1990) Gene-enzyme relationship in the sulfate assimilation pathway of Saccharomyces cerevisiae. Study of the 3'-phosphoadenylylsulfate reductase structural gene. J. Biol. Chem. 265 15518-24 PubMed GONUTS page
- ↑ 5.0 5.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
