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YEAST:MEP2

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Species (Taxon ID) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292)
Gene Name(s) MEP2 (synonyms: AMT2)
Protein Name(s) Ammonium transporter MEP2
External Links
UniProt P41948
EMBL X83608
Z46843
Z71418
BK006947
PIR S51089
RefSeq NP_014257.1
ProteinModelPortal P41948
SMR P41948
BioGrid 35685
DIP DIP-4340N
IntAct P41948
MINT MINT-568645
STRING 4932.YNL142W
BindingDB P41948
ChEMBL CHEMBL1741183
TCDB 1.A.11.3.2
PaxDb P41948
EnsemblFungi [example_ID YNL142W]
GeneID 855580
KEGG sce:YNL142W
CYGD YNL142w
SGD S000005086
eggNOG COG0004
GeneTree ENSGT00530000064546
HOGENOM HOG000017736
InParanoid P41948
KO K03320
OMA CATIAWT
OrthoDB EOG79SF67
BioCyc YEAST:G3O-33160-MONOMER
NextBio 979706
Proteomes UP000002311
Genevestigator P41948
GO GO:0016021
GO:0005886
GO:0008519
GO:0015696
GO:0019740
GO:0007124
Gene3D 1.10.3430.10
InterPro IPR029020
IPR001905
IPR018047
IPR024041
PANTHER PTHR11730
Pfam PF00909
SUPFAM SSF111352
TIGRFAMs TIGR00836
PROSITE PS01219

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0019740

nitrogen utilization

PMID:9234685[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0015696

ammonium transport

PMID:9234685[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0008519

ammonium transmembrane transporter activity

PMID:9234685[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0008519

ammonium transmembrane transporter activity

PMID:9234685[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0007124

pseudohyphal growth

PMID:9482721[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

GO:0005886

plasma membrane

PMID:11069679[3]

ECO:0000314

C

complete

part_of

GO:0005886

plasma membrane

PMID:24124599[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:11069679[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0019740

nitrogen utilization

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000198228
SGD:S000003353
SGD:S000005086
SGD:S000006342
UniProtKB:G5EB09
UniProtKB:G5EB13

P

Seeded From UniProt

complete

enables

GO:0008519

ammonium transmembrane transporter activity

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11821
PANTHER:PTN000198228
PomBase:SPAC2E1P3.02c
PomBase:SPAC664.14
PomBase:SPCPB1C11.01
SGD:S000003353
SGD:S000005086
SGD:S000006342
TAIR:locus:2042917
UniProtKB:A0A1D8PJF2
UniProtKB:G5EB09
UniProtKB:G5EB13
UniProtKB:Q59UP8

F

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11821
PANTHER:PTN000198228

C

Seeded From UniProt

complete

enables

GO:0008519

ammonium transmembrane transporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001905
InterPro:IPR018047
InterPro:IPR024041

F

Seeded From UniProt

complete

involved_in

GO:0015696

ammonium transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR024041

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001905
InterPro:IPR018047
InterPro:IPR024041

C

Seeded From UniProt

complete

involved_in

GO:0072488

ammonium transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001905
InterPro:IPR018047

P

Seeded From UniProt

complete

involved_in

GO:0015696

ammonium transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0924

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Marini, AM et al. (1997) A family of ammonium transporters in Saccharomyces cerevisiae. Mol. Cell. Biol. 17 4282-93 PubMed GONUTS page
  2. Lorenz, MC & Heitman, J (1998) The MEP2 ammonium permease regulates pseudohyphal differentiation in Saccharomyces cerevisiae. EMBO J. 17 1236-47 PubMed GONUTS page
  3. 3.0 3.1 Marini, AM & André, B (2000) In vivo N-glycosylation of the mep2 high-affinity ammonium transporter of Saccharomyces cerevisiae reveals an extracytosolic N-terminus. Mol. Microbiol. 38 552-64 PubMed GONUTS page
  4. Scharff-Poulsen, P & Pedersen, PA (2013) Saccharomyces cerevisiae-based platform for rapid production and evaluation of eukaryotic nutrient transporters and transceptors for biochemical studies and crystallography. PLoS ONE 8 e76851 PubMed GONUTS page
  5. 5.0 5.1 5.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page