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YEAST:MAS5
Contents
Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
Gene Name(s) | YDJ1 (synonyms: MAS5) | |
Protein Name(s) | Mitochondrial protein import protein MAS5
Yeast dnaJ protein 1 | |
External Links | ||
UniProt | P25491 | |
EMBL | X56560 S74758 U12141 Z71340 BK006947 | |
PIR | S26703 | |
RefSeq | NP_014335.1 | |
PDB | 1NLT 1XAO | |
PDBsum | 1NLT 1XAO | |
ProteinModelPortal | P25491 | |
SMR | P25491 | |
BioGrid | 35759 | |
DIP | DIP-2251N | |
IntAct | P25491 | |
MINT | MINT-603538 | |
STRING | 4932.YNL064C | |
MaxQB | P25491 | |
PaxDb | P25491 | |
PeptideAtlas | P25491 | |
EnsemblFungi | [example_ID YNL064C] | |
GeneID | 855661 | |
KEGG | sce:YNL064C | |
CYGD | YNL064c | |
SGD | S000005008 | |
eggNOG | COG0484 | |
GeneTree | ENSGT00490000043321 | |
HOGENOM | HOG000226718 | |
InParanoid | P25491 | |
KO | K09503 | |
OMA | HVSGDWL | |
OrthoDB | EOG77M90H | |
BioCyc | YEAST:G3O-33094-MONOMER | |
EvolutionaryTrace | P25491 | |
NextBio | 979926 | |
PRO | PR:P25491 | |
Proteomes | UP000002311 | |
Genevestigator | P25491 | |
GO | GO:0005829 GO:0048471 GO:0072380 GO:0005524 GO:0001671 GO:0046872 GO:0051082 GO:0006458 GO:0030433 GO:0032781 GO:0042026 GO:0045047 GO:0006626 GO:0009408 | |
Gene3D | 1.10.287.110 2.10.230.10 | |
HAMAP | MF_01152 | |
InterPro | IPR012724 IPR002939 IPR001623 IPR018253 IPR008971 IPR001305 | |
Pfam | PF01556 PF00226 PF00684 | |
PRINTS | PR00625 | |
SMART | SM00271 | |
SUPFAM | SSF46565 SSF49493 SSF57938 | |
PROSITE | PS00636 PS50076 PS51188 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
part_of |
GO:0005829 |
cytosol |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0051131 |
chaperone-mediated protein complex assembly |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0035719 |
tRNA import into nucleus |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
happens_during:(GO:0009267) |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006511 |
ubiquitin-dependent protein catabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
happens_during:(GO:0034605) |
Seeded From UniProt |
complete | ||
part_of |
GO:0072380 |
TRC complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0051082 |
unfolded protein binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0048471 |
perinuclear region of cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045047 |
protein targeting to ER |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0042026 |
protein refolding |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030433 |
ubiquitin-dependent ERAD pathway |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030433 |
ubiquitin-dependent ERAD pathway |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006626 |
protein targeting to mitochondrion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006458 |
'de novo' protein folding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0001671 |
ATPase activator activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0001671 |
ATPase activator activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001531327 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0032781 |
positive regulation of ATPase activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0001671 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0032781 |
positive regulation of ATPase activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0001671 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006457 |
protein folding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0009408 |
response to heat |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0031072 |
heat shock protein binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0051082 |
unfolded protein binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0015031 |
protein transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0048471 |
perinuclear region of cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Yofe, I et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat. Methods 13 371-378 PubMed GONUTS page
- ↑ Weaver, AJ et al. (2000) Crystal structure and activity of human p23, a heat shock protein 90 co-chaperone. J. Biol. Chem. 275 23045-52 PubMed GONUTS page
- ↑ Takano, A et al. (2015) Cytosolic Hsp70 and co-chaperones constitute a novel system for tRNA import into the nucleus. Elife 4 PubMed GONUTS page
- ↑ Fang, NN et al. (2014) Rsp5/Nedd4 is the main ubiquitin ligase that targets cytosolic misfolded proteins following heat stress. Nat. Cell Biol. 16 1227-37 PubMed GONUTS page
- ↑ Wang, F et al. (2010) A chaperone cascade sorts proteins for posttranslational membrane insertion into the endoplasmic reticulum. Mol. Cell 40 159-71 PubMed GONUTS page
- ↑ Lu, Z & Cyr, DM (1998) Protein folding activity of Hsp70 is modified differentially by the hsp40 co-chaperones Sis1 and Ydj1. J. Biol. Chem. 273 27824-30 PubMed GONUTS page
- ↑ 7.0 7.1 Caplan, AJ & Douglas, MG (1991) Characterization of YDJ1: a yeast homologue of the bacterial dnaJ protein. J. Cell Biol. 114 609-21 PubMed GONUTS page
- ↑ Caplan, AJ et al. (1992) YDJ1p facilitates polypeptide translocation across different intracellular membranes by a conserved mechanism. Cell 71 1143-55 PubMed GONUTS page
- ↑ Glover, JR & Lindquist, S (1998) Hsp104, Hsp70, and Hsp40: a novel chaperone system that rescues previously aggregated proteins. Cell 94 73-82 PubMed GONUTS page
- ↑ Huyer, G et al. (2004) Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein. J. Biol. Chem. 279 38369-78 PubMed GONUTS page
- ↑ 11.0 11.1 Youker, RT et al. (2004) Distinct roles for the Hsp40 and Hsp90 molecular chaperones during cystic fibrosis transmembrane conductance regulator degradation in yeast. Mol. Biol. Cell 15 4787-97 PubMed GONUTS page
- ↑ Atencio, DP & Yaffe, MP (1992) MAS5, a yeast homolog of DnaJ involved in mitochondrial protein import. Mol. Cell. Biol. 12 283-91 PubMed GONUTS page
- ↑ Meacham, GC et al. (1999) Mutations in the yeast Hsp40 chaperone protein Ydj1 cause defects in Axl1 biogenesis and pro-a-factor processing. J. Biol. Chem. 274 34396-402 PubMed GONUTS page
- ↑ Cyr, DM & Douglas, MG (1994) Differential regulation of Hsp70 subfamilies by the eukaryotic DnaJ homologue YDJ1. J. Biol. Chem. 269 9798-804 PubMed GONUTS page
- ↑ Cyr, DM et al. (1992) Regulation of Hsp70 function by a eukaryotic DnaJ homolog. J. Biol. Chem. 267 20927-31 PubMed GONUTS page
- ↑ Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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