GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

YEAST:KRE2

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292)
Gene Name(s) KRE2 (synonyms: MNT1)
Protein Name(s) Glycolipid 2-alpha-mannosyltransferase

Alpha-1,2-mannosyltransferase

External Links
UniProt P27809
EMBL M81110
X62647
U33050
Z29988
BK006938
PIR S32592
RefSeq NP_010771.1
PDB 1S4N
1S4O
1S4P
PDBsum 1S4N
1S4O
1S4P
ProteinModelPortal P27809
SMR P27809
BioGrid 32535
DIP DIP-5373N
IntAct P27809
MINT MINT-514227
STRING 4932.YDR483W
CAZy GT15
MaxQB P27809
PaxDb P27809
PeptideAtlas P27809
PRIDE P27809
EnsemblFungi [example_ID YDR483W]
GeneID 852094
KEGG sce:YDR483W
CYGD YDR483w
SGD S000002891
eggNOG COG5020
GeneTree ENSGT00390000000831
HOGENOM HOG000160667
InParanoid P27809
KO K10967
OMA HFHCDID
OrthoDB EOG779P83
BioCyc YEAST:G3O-30008-MONOMER
UniPathway UPA00378
EvolutionaryTrace P27809
NextBio 970427
Proteomes UP000002311
Genevestigator P27809
GO GO:0005794
GO:0000139
GO:0016021
GO:0000026
GO:0000032
GO:0097502
GO:0006491
GO:0006493
Gene3D 3.90.550.10
InterPro IPR002685
IPR029044
Pfam PF01793
PIRSF PIRSF018153
SUPFAM SSF53448

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0000329

fungal-type vacuole membrane

PMID:26928762[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

GO:0005797

Golgi medial cisterna

PMID:7490293[2]

ECO:0000314

C

Figure 5 shows Kre2p Golgi localization overlaps with that of the medial-Golgi mannosyltransferase Mnnlp.

complete
CACAO 11726

involved_in

GO:0006493

protein O-linked glycosylation

PMID:1495972[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006491

N-glycan processing

PMID:1495972[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

PMID:7490293[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0000032

cell wall mannoprotein biosynthetic process

PMID:1541391[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0000026

alpha-1,2-mannosyltransferase activity

PMID:1550992[5]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006493

protein O-linked glycosylation

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000779407
SGD:S000000409
SGD:S000002891
SGD:S000005625

P

Seeded From UniProt

complete

involved_in

GO:0006487

protein N-linked glycosylation

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

CGD:CAL0000188769
PANTHER:PTN001579360
SGD:S000001769
SGD:S000003675
SGD:S000005625
SGD:S000005974
UniProtKB:A0A1D8PH51

P

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001579360
SGD:S000001769
SGD:S000002891
SGD:S000003675
SGD:S000005625
UniProtKB:Q4WV44

C

Seeded From UniProt

complete

involved_in

GO:0000032

cell wall mannoprotein biosynthetic process

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001579360
SGD:S000001769
SGD:S000002891
SGD:S000003675
UniProtKB:A0A1D8PH51

P

Seeded From UniProt

complete

enables

GO:0000026

alpha-1,2-mannosyltransferase activity

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

CGD:CAL0000188662
PANTHER:PTN001579360
PomBase:SPBC19C7.12c
SGD:S000002891
SGD:S000005625
UniProtKB:A0A1D8PH51

F

Seeded From UniProt

complete

involved_in

GO:0097502

mannosylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0000030

P

Seeded From UniProt

complete

involved_in

GO:0097502

mannosylation

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0000026

P

Seeded From UniProt

complete

involved_in

GO:0097502

mannosylation

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0000026

P

Seeded From UniProt

complete

enables

GO:0000030

mannosyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002685

F

Seeded From UniProt

complete

involved_in

GO:0006486

protein glycosylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002685

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002685

C

Seeded From UniProt

complete

enables

GO:0016757

transferase activity, transferring glycosyl groups

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0328

F

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0333

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0000139

Golgi membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0134

C

Seeded From UniProt

complete

involved_in

GO:0006486

protein glycosylation

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00378

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Yofe, I et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat. Methods 13 371-378 PubMed GONUTS page
  2. 2.0 2.1 Lussier, M et al. (1995) Localization and targeting of the Saccharomyces cerevisiae Kre2p/Mnt1p alpha 1,2-mannosyltransferase to a medial-Golgi compartment. J. Cell Biol. 131 913-27 PubMed GONUTS page
  3. 3.0 3.1 Häusler, A et al. (1992) Yeast glycoprotein biosynthesis: MNT1 encodes an alpha-1,2-mannosyltransferase involved in O-glycosylation. Proc. Natl. Acad. Sci. U.S.A. 89 6846-50 PubMed GONUTS page
  4. Hill, K et al. (1992) Yeast KRE2 defines a new gene family encoding probable secretory proteins, and is required for the correct N-glycosylation of proteins. Genetics 130 273-83 PubMed GONUTS page
  5. Häusler, A & Robbins, PW (1992) Glycosylation in Saccharomyces cerevisiae: cloning and characterization of an alpha-1,2-mannosyltransferase structural gene. Glycobiology 2 77-84 PubMed GONUTS page
  6. 6.0 6.1 6.2 6.3 6.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page