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YEAST:KPYK1
Contents
Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
Gene Name(s) | CDC19 (synonyms: PYK1) | |
Protein Name(s) | Pyruvate kinase 1
PK 1 cell division cycle protein 19 | |
External Links | ||
UniProt | P00549 | |
EMBL | V01321 X14400 AY949862 AY949863 AY949864 AY949865 AY949866 AY949867 AY949868 AY949869 AY949870 AY949871 AY949872 AY949873 AY949874 AY949875 AY949876 AY949877 AY949878 AY949879 AY949880 AY949881 AY949882 AY949883 AY949884 AY949885 AY949886 AY949887 AY949888 AY949889 AY949890 U12980 AY693107 BK006935 | |
PIR | S05764 | |
RefSeq | NP_009362.1 | |
PDB | 1A3W 1A3X | |
PDBsum | 1A3W 1A3X | |
ProteinModelPortal | P00549 | |
SMR | P00549 | |
BioGrid | 31727 | |
DIP | DIP-4124N | |
IntAct | P00549 | |
MINT | MINT-565419 | |
STRING | 4932.YAL038W | |
COMPLUYEAST-2DPAGE | P00549 | |
MaxQB | P00549 | |
PaxDb | P00549 | |
PeptideAtlas | P00549 | |
EnsemblFungi | [example_ID YAL038W] | |
GeneID | 851193 | |
KEGG | sce:YAL038W | |
CYGD | YAL038w | |
SGD | S000000036 | |
eggNOG | COG0469 | |
GeneTree | ENSGT00390000008859 | |
HOGENOM | HOG000021559 | |
InParanoid | P00549 | |
KO | K00873 | |
OMA | ISKKCAY | |
OrthoDB | EOG7M6DJC | |
BioCyc | YEAST:YAL038W-MONOMER | |
Reactome | REACT_229625 REACT_237953 REACT_241476 | |
SABIO-RK | P00549 | |
UniPathway | UPA00109 | |
EvolutionaryTrace | P00549 | |
NextBio | 968037 | |
Proteomes | UP000002311 | |
Genevestigator | P00549 | |
GO | GO:0005737 GO:0005524 GO:0000287 GO:0030955 GO:0004743 GO:0006096 GO:0006090 | |
Gene3D | 2.40.33.10 3.20.20.60 3.40.1380.20 | |
InterPro | IPR001697 IPR015813 IPR011037 IPR015794 IPR018209 IPR015793 IPR015795 IPR015806 | |
PANTHER | PTHR11817 | |
Pfam | PF00224 PF02887 | |
PRINTS | PR01050 | |
SUPFAM | SSF50800 SSF51621 SSF52935 | |
TIGRFAMs | TIGR01064 | |
PROSITE | PS00110 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0004743 |
pyruvate kinase activity |
ECO:0000316 |
|
F |
Figure 1B and 1C Pyruvate kinase activity of TEFpr-PYK1 and CYCpr-PYK1. TEFpr is a strong promotor, CYCpr is a weak promotor. |
complete | ||||
GO:0006098 |
pentose-phosphate shunt |
ECO:0000314 |
P |
Figure 5B Cells with low PYK activity have increased concentrations of PPP intermediates |
complete | |||||
part_of |
GO:0005886 |
plasma membrane |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006096 |
glycolytic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006090 |
pyruvate metabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0004743 |
pyruvate kinase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004743 |
pyruvate kinase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0032869 |
cellular response to insulin stimulus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000212861 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006096 |
glycolytic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10803 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000212670 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0004743 |
pyruvate kinase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10803 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0000287 |
magnesium ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003824 |
catalytic activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004743 |
pyruvate kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001697 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006096 |
glycolytic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001697 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0030955 |
potassium ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004743 |
pyruvate kinase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003824 |
catalytic activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0008152 |
metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006096 |
glycolytic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0324 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0016310 |
phosphorylation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0016301 |
kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Grüning, NM et al. (2011) Pyruvate kinase triggers a metabolic feedback loop that controls redox metabolism in respiring cells. Cell Metab. 14 415-27 PubMed GONUTS page
- ↑ Delom, F et al. (2006) The plasma membrane proteome of Saccharomyces cerevisiae and its response to the antifungal calcofluor. Proteomics 6 3029-39 PubMed GONUTS page
- ↑ Finnigan, GC et al. (2016) Detection of protein-protein interactions at the septin collar in Saccharomyces cerevisiae using a tripartite split-GFP system. Mol. Biol. Cell 27 2708-25 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Sprague, GF Jr (1977) Isolation and characterization of a Saccharomyces cerevisiae mutant deficient in pyruvate kinase activity. J. Bacteriol. 130 232-41 PubMed GONUTS page
- ↑ Jablonowski, D et al. (2004) The yeast elongator histone acetylase requires Sit4-dependent dephosphorylation for toxin-target capacity. Mol. Biol. Cell 15 1459-69 PubMed GONUTS page
- ↑ Portela, P et al. (2002) In vivo and in vitro phosphorylation of two isoforms of yeast pyruvate kinase by protein kinase A. J. Biol. Chem. 277 30477-87 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 7.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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