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YEAST:HXKG

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Species (Taxon ID) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292)
Gene Name(s) GLK1 (synonyms: HOR3)
Protein Name(s) Glucokinase-1

Glucose kinase 1 GLK-1

External Links
UniProt P17709
EMBL M24077
X59720
BK006937
PIR JT0482
RefSeq NP_009890.1
ProteinModelPortal P17709
SMR P17709
BioGrid 30943
DIP DIP-525N
IntAct P17709
MINT MINT-401461
STRING 4932.YCL040W
MaxQB P17709
PaxDb P17709
PeptideAtlas P17709
EnsemblFungi [example_ID YCL040W]
GeneID 850317
KEGG sce:YCL040W
CYGD YCL040w
SGD S000000545
eggNOG COG5026
GeneTree ENSGT00390000017159
HOGENOM HOG000162670
InParanoid P17709
KO K00844
OMA GEVEIGC
OrthoDB EOG79SF68
BioCyc MetaCyc:MONOMER-5982
YEAST:YCL040W-MONOMER
Reactome REACT_237953
REACT_253318
REACT_260359
SABIO-RK P17709
NextBio 965721
Proteomes UP000002311
Genevestigator P17709
GO GO:0005524
GO:0004340
GO:0051156
GO:0046323
GO:0006006
GO:0006096
GO:0006013
InterPro IPR001312
IPR022673
IPR019807
IPR022672
PANTHER PTHR19443
Pfam PF00349
PF03727
PRINTS PR00475
PROSITE PS00378

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005829

cytosol

PMID:14562095[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:16622836[2]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0046323

glucose import

PMID:6300872[3]

ECO:0000316

genetic interaction evidence used in manual assertion

SGD:S000001949
SGD:S000003222

P

Seeded From UniProt

complete

involved_in

GO:0006096

glycolytic process

PMID:8501032[4]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006013

mannose metabolic process

PMID:237183[5]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006006

glucose metabolic process

PMID:6300872[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004340

glucokinase activity

PMID:6341351[6]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004340

glucokinase activity

PMID:8501032[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0019158

mannokinase activity

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000455350
PomBase:SPAC24H6.04
PomBase:SPAC4F8.07c

F

Seeded From UniProt

complete

enables

GO:0008865

fructokinase activity

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000455350
PomBase:SPAC24H6.04
PomBase:SPAC4F8.07c
TAIR:locus:2008031
TAIR:locus:2087590
TAIR:locus:2119931
TAIR:locus:2137564
TAIR:locus:2202410
UniProtKB:P93834
UniProtKB:Q4WHC3

F

Seeded From UniProt

complete

involved_in

GO:0006096

glycolytic process

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000455350
RGD:2670
RGD:2796
SGD:S000000545
SGD:S000001949
SGD:S000003222

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1270854
MGI:MGI:96103
PANTHER:PTN000455350
RGD:2670
RGD:2796
SGD:S000003222
UniProtKB:C6KT76
UniProtKB:P35557

C

Seeded From UniProt

complete

enables

GO:0004340

glucokinase activity

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1270854
MGI:MGI:96103
PANTHER:PTN000455350
PomBase:SPAC24H6.04
PomBase:SPAC4F8.07c
RGD:2670
RGD:2796
SGD:S000000545
TAIR:locus:2008031
TAIR:locus:2087590
TAIR:locus:2119931
TAIR:locus:2137564
TAIR:locus:2202410
UniProtKB:P35557
UniProtKB:P93834
UniProtKB:Q4WCS2
UniProtKB:Q4WHC3
UniProtKB:Q5W676
UniProtKB:Q8LQ68

F

Seeded From UniProt

complete

involved_in

GO:0001678

cellular glucose homeostasis

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1270854
PANTHER:PTN000455350
RGD:2670

P

Seeded From UniProt

complete

involved_in

GO:0046835

carbohydrate phosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004396

P

Seeded From UniProt

complete

involved_in

GO:0046835

carbohydrate phosphorylation

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0019158

P

Seeded From UniProt

complete

involved_in

GO:0046835

carbohydrate phosphorylation

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0008865

P

Seeded From UniProt

complete

involved_in

GO:0051156

glucose 6-phosphate metabolic process

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004340

P

Seeded From UniProt

complete

involved_in

GO:0051156

glucose 6-phosphate metabolic process

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004340

P

Seeded From UniProt

complete

involved_in

GO:0051156

glucose 6-phosphate metabolic process

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004340

P

Seeded From UniProt

complete

involved_in

GO:0051156

glucose 6-phosphate metabolic process

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004340

P

Seeded From UniProt

complete

involved_in

GO:0001678

cellular glucose homeostasis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001312

P

Seeded From UniProt

complete

enables

GO:0004396

hexokinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001312
InterPro:IPR019807

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001312
InterPro:IPR019807
InterPro:IPR022672
InterPro:IPR022673

F

Seeded From UniProt

complete

enables

GO:0005536

glucose binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001312

F

Seeded From UniProt

complete

involved_in

GO:0005975

carbohydrate metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001312
InterPro:IPR022672
InterPro:IPR022673

P

Seeded From UniProt

complete

involved_in

GO:0006096

glycolytic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR019807

P

Seeded From UniProt

complete

enables

GO:0016773

phosphotransferase activity, alcohol group as acceptor

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR022672
InterPro:IPR022673

F

Seeded From UniProt

complete

enables

GO:0004340

glucokinase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.1.2

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

involved_in

GO:0006096

glycolytic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0324

P

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ Huh, WK et al. (2003) Global analysis of protein localization in budding yeast. Nature 425 686-91 PubMed GONUTS page
  2. ↑ Delom, F et al. (2006) The plasma membrane proteome of Saccharomyces cerevisiae and its response to the antifungal calcofluor. Proteomics 6 3029-39 PubMed GONUTS page
  3. ↑ 3.0 3.1 Bisson, LF & Fraenkel, DG (1983) Involvement of kinases in glucose and fructose uptake by Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. U.S.A. 80 1730-4 PubMed GONUTS page
  4. ↑ 4.0 4.1 Clifton, D et al. (1993) Functional studies of yeast glucokinase. J. Bacteriol. 175 3289-94 PubMed GONUTS page
  5. ↑ Maitra, PK (1975) Glucokinase from yeast. Meth. Enzymol. 42 25-30 PubMed GONUTS page
  6. ↑ Walsh, RB et al. (1983) Cloning of genes that complement yeast hexokinase and glucokinase mutants. J. Bacteriol. 154 1002-4 PubMed GONUTS page
  7. ↑ 7.0 7.1 7.2 7.3 7.4 7.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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