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YEAST:DCR2

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Species (Taxon ID) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292)
Gene Name(s) DCR2
Protein Name(s) Phosphatase DCR2

Dosage-dependent cell cycle regulator 2

External Links
UniProt Q05924
EMBL U19103
BK006945
PIR S51379
RefSeq NP_013465.1
ProteinModelPortal Q05924
BioGrid 31622
IntAct Q05924
MINT MINT-3380862
STRING 4932.YLR361C
MaxQB Q05924
PaxDb Q05924
EnsemblFungi [example_ID YLR361C]
GeneID 851075
KEGG sce:YLR361C
CYGD YLR361c
SGD S000004353
eggNOG COG1409
GeneTree ENSGT00750000118740
HOGENOM HOG000192313
InParanoid Q05924
OMA YGGTERR
OrthoDB EOG70KGZ6
BioCyc YEAST:G3O-32432-MONOMER
NextBio 967726
Proteomes UP000002311
Genevestigator Q05924
GO GO:0005737
GO:0005524
GO:0016788
GO:0004721
GO:0042578
GO:0007049
GO:0030968
GO:0006470
GO:0007089
Gene3D 3.60.21.10
InterPro IPR004843
IPR029052
Pfam PF00149
SUPFAM SSF56300

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0000324

fungal-type vacuole

PMID:26928762[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0004721

phosphoprotein phosphatase activity

PMID:16990850[2]

ECO:0000314

direct assay evidence used in manual assertion

F

has_direct_input:(UniProtKB:P32361)

Seeded From UniProt

complete

involved_in

GO:1900102

negative regulation of endoplasmic reticulum unfolded protein response

PMID:16990850[2]

ECO:0000316

genetic interaction evidence used in manual assertion

SGD:S000001121

P

Seeded From UniProt

complete

involved_in

GO:1900102

negative regulation of endoplasmic reticulum unfolded protein response

PMID:16990850[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0016788

hydrolase activity, acting on ester bonds

PMID:15590836[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0016788

hydrolase activity, acting on ester bonds

PMID:15590836[3]

ECO:0000250

sequence similarity evidence used in manual assertion

F

Seeded From UniProt

Missing: with/from

involved_in

GO:0007089

traversing start control point of mitotic cell cycle

PMID:15590836[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006470

protein dephosphorylation

PMID:17673172[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

has_direct_input:(UniProtKB:P38634)

Seeded From UniProt

complete

involved_in

GO:0006470

protein dephosphorylation

PMID:17673172[4]

ECO:0000314

direct assay evidence used in manual assertion

P

has_direct_input:(UniProtKB:P38634)

Seeded From UniProt

complete

involved_in

GO:0006470

protein dephosphorylation

PMID:16990850[2]

ECO:0000314

direct assay evidence used in manual assertion

P

has_direct_input:(UniProtKB:P32361)

Seeded From UniProt

complete

enables

GO:0004721

phosphoprotein phosphatase activity

PMID:17673172[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

has_direct_input:(UniProtKB:P38634)

Seeded From UniProt

complete

enables

GO:0004721

phosphoprotein phosphatase activity

PMID:17673172[4]

ECO:0000314

direct assay evidence used in manual assertion

F

has_direct_input:(UniProtKB:P38634)

Seeded From UniProt

complete

enables

GO:0016788

hydrolase activity, acting on ester bonds

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000793892
SGD:S000004353

F

Seeded From UniProt

complete

enables

GO:0004721

phosphoprotein phosphatase activity

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001286392
SGD:S000004353

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004843

F

Seeded From UniProt

complete

involved_in

GO:0007049

cell cycle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0131

P

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Yofe, I et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat. Methods 13 371-378 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Guo, J & Polymenis, M (2006) Dcr2 targets Ire1 and downregulates the unfolded protein response in Saccharomyces cerevisiae. EMBO Rep. 7 1124-7 PubMed GONUTS page
  3. 3.0 3.1 3.2 Pathak, R et al. (2004) Gid8p (Dcr1p) and Dcr2p function in a common pathway to promote START completion in Saccharomyces cerevisiae. Eukaryotic Cell 3 1627-38 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Pathak, R et al. (2007) The Dcr2p phosphatase destabilizes Sic1p in Saccharomyces cerevisiae. Biochem. Biophys. Res. Commun. 361 700-4 PubMed GONUTS page
  5. 5.0 5.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page