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YEAS8:C8ZBW3

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Species (Taxon ID) Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse)(Baker's yeast). (643680)
Gene Name(s) No Information Provided.
Protein Name(s) Jen1p (ECO:0000313 with EMBL:CAY80879.1)
External Links
UniProt C8ZBW3
EMBL FN393077
OrthoDB EOG78H430
Proteomes UP000000286
GO GO:0016021
GO:0015144
InterPro IPR020846
IPR004742
IPR005828
Pfam PF00083
SUPFAM SSF103473
TIGRFAMs TIGR00891
PROSITE PS50850

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0015296

anion:cation symporter activity

PMID:20861301[1]

ECO:0000315

F

Fig 3.

In galactose containing medium, WT cells exhibited increased selenite accumulation compared with the JEN1 knock out strain QZ1. Cells of QZ1 constitutively expressing JEN1 from plasmid pJEN1 accumulated more selenite than the WT and was insensitive to glucose repression. When WT cells were cultured in glucose to repress JEN1, selenite uptake was comparable to the JEN1 knock out strain.

Fig 5.

Selenite uptake was pH-dependent, with maximum transport occurring at lower pH, consistent with proton dependence. The ionophore FCCP and protonophore nigericin, both of which dissipate the proton gradient, strongly inhibited selenite transport via Jen1p. These results are consistent with selenite being taken up in a proton-coupled manner, dependent on pH.

complete

enables

GO:0015136

sialic acid transmembrane transporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004742

F

Seeded From UniProt

complete

involved_in

GO:0015739

sialic acid transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004742

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004742
InterPro:IPR005828

C

Seeded From UniProt

complete

enables

GO:0022857

transmembrane transporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005828

F

Seeded From UniProt

complete

involved_in

GO:0055085

transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005828

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. McDermott, JR et al. (2010) Jen1p: a high affinity selenite transporter in yeast. Mol. Biol. Cell 21 3934-41 PubMed GONUTS page