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XENTR:Q0IHV4

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Species (Taxon ID) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis). (8364)
Gene Name(s) No Information Provided.
Protein Name(s) Microtubule-associated protein (ECO:0000256 with RuleBase:RU000686)
External Links
UniProt Q0IHV4
EMBL AAMC01128483
AAMC01128484
AAMC01128485
AAMC01128486
AAMC01128487
AAMC01128488
AAMC01128489
AAMC01128490
BC122954
UniGene Str.28128
Ensembl ENSXETT00000003431
Xenbase XB-GENE-5945202
GeneTree ENSGT00530000063491
HOVERGEN HBG000991
Proteomes UP000008143
ExpressionAtlas Q0IHV4
GO GO:0005737
GO:0005874
InterPro IPR027324
IPR001084
PANTHER PTHR11501
Pfam PF00418
PROSITE PS00229
PS51491

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0050321

tau-protein kinase activity

PMID:1376245[1]

ECO:0000314

F

Figure 1 shows that p34-cycB is not likely to be responsible for the transformation of tau.

complete
CACAO 9450

GO:0050321

tau-protein kinase activity

PMID:1376245[1]

ECO:0000314

F

Figure 2 shows that the effects of the MAP kinases were indistinguishable from the brain extract, suggesting that a similar enzyme was dominant in the extract

complete
CACAO 9451

GO:0050321

tau-protein kinase activity

PMID:1376245[1]

ECO:0000314

F

Figure 3 further confirmed that a MAP kinase was present in brain extract that led to a phosphorylation of tyrosine, which confirmed it was present in the brain extract

complete
CACAO 9457

GO:0050321

tau-protein kinase activity

PMID:1376245[1]

ECO:0000314

F

Figure 7 shows that the time course of phorphorylation of tau with MAP kinase is similar to the results obtained with the brain extract, except the results increased significantly with purification

complete
CACAO 9464

GO:0050321

tau-protein kinase activity

PMID:1376245[1]

ECO:0000314

F

Figure 8 shows that the effect of MAP kinase can also be demonstrated directly with PHF tau from an Alzheimer brain.

complete
CACAO 9465

part_of

GO:0043005

neuron projection

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97175
PANTHER:PTN000161190
RGD:3044
RGD:69329
WB:WBGene00004212

C

Seeded From UniProt

complete

involved_in

GO:0031175

neuron projection development

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000161190
UniProtKB:P11137

P

Seeded From UniProt

complete

enables

GO:0008017

microtubule binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0266579
MGI:MGI:97175
MGI:MGI:97178
MGI:MGI:97180
PANTHER:PTN000161190
RGD:3044
RGD:69329
UniProtKB:P10636
WB:WBGene00004212

F

Seeded From UniProt

complete

involved_in

GO:0000226

microtubule cytoskeleton organization

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0266579
MGI:MGI:97175
MGI:MGI:97178
MGI:MGI:97180
PANTHER:PTN000161190
UniProtKB:P10636

P

Seeded From UniProt

complete

involved_in

GO:0001578

microtubule bundle formation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030797

P

Seeded From UniProt

complete

enables

GO:0015631

tubulin binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001084

F

Seeded From UniProt

complete

involved_in

GO:0021954

central nervous system neuron development

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030797

P

Seeded From UniProt

complete

part_of

GO:0005856

cytoskeleton

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0206

C

Seeded From UniProt

complete

part_of

GO:0005874

microtubule

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0493

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

part_of

GO:0005856

cytoskeleton

GO_REF:0000040

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-SubCell:SL-0090

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Drewes, G et al. (1992) Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer-like state. EMBO J. 11 2131-8 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page