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VIBVU:Q8DES3
Contents
| Species (Taxon ID) | Vibrio vulnificus (strain CMCP6). (216895) | |
| Gene Name(s) | No Information Provided. | |
| Protein Name(s) | Transcriptional activator HlyU (ECO:0000313 with EMBL:AAO09030.1) | |
| External Links | ||
| UniProt | Q8DES3 | |
| EMBL | AE016795 | |
| RefSeq | NP_759503.1 | |
| PDB | 3JTH | |
| PDBsum | 3JTH | |
| ProteinModelPortal | Q8DES3 | |
| MINT | MINT-7710061 | |
| STRING | 216895.VV1_0512 | |
| EnsemblBacteria | AAO09030 | |
| GeneID | 1177465 | |
| KEGG | vvu:VV1_0512 | |
| PATRIC | 20157840 | |
| eggNOG | COG0640 | |
| HOGENOM | HOG000144506 | |
| OMA | MQQRADH | |
| OrthoDB | EOG6B3684 | |
| BioCyc | VVUL216895:GIYM-473-MONOMER | |
| EvolutionaryTrace | Q8DES3 | |
| Proteomes | UP000002275 | |
| GO | GO:0003677 GO:0042802 GO:0003700 GO:0006351 | |
| Gene3D | 1.10.10.10 | |
| InterPro | IPR001845 IPR011991 | |
| Pfam | PF01022 | |
| PRINTS | PR00778 | |
| SMART | SM00418 | |
| PROSITE | PS50987 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
ECO:0000314 |
P |
Fig. 2: mutations in hlyU gene decrease cytotoxicity, meaning hlyU is a positive transcriptional regulator of cytotoxicity genes. |
complete | |||||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Liu, M et al. (2007) The HlyU protein is a positive regulator of rtxA1, a gene responsible for cytotoxicity and virulence in the human pathogen Vibrio vulnificus. Infect. Immun. 75 3282-9 PubMed GONUTS page
- ↑ Liu, M et al. (2011) Homodimerization and binding of specific domains to the target DNA are essential requirements for HlyU to regulate expression of the virulence gene rtxA1, encoding the repeat-in-toxin protein in the human pathogen Vibrio vulnificus. J. Bacteriol. 193 6895-901 PubMed GONUTS page
- ↑ Nishi, K et al. (2010) Crystal structure of the transcriptional activator HlyU from Vibrio vulnificus CMCP6. FEBS Lett. 584 1097-102 PubMed GONUTS page
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