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VIBPA:VOPS
Contents
| Species (Taxon ID) | Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633). (223926) | |
| Gene Name(s) | vopS | |
| Protein Name(s) | Adenosine monophosphate-protein transferase VopS
AMPylator VopS Vibrio outer protein S | |
| External Links | ||
| UniProt | Q87P32 | |
| EMBL | BA000031 | |
| RefSeq | NP_798065.1 | |
| PDB | 3LET | |
| PDBsum | 3LET | |
| STRING | 223926.VP1686 | |
| EnsemblBacteria | BAC59949 | |
| GeneID | 1189193 | |
| KEGG | vpa:VP1686 | |
| PATRIC | 20141546 | |
| HOGENOM | HOG000290317 | |
| OMA | HGFTDGN | |
| OrthoDB | EOG6G4VRM | |
| BioCyc | VPAR223926:GHK4-1737-MONOMER | |
| Proteomes | UP000002493 | |
| GO | GO:0005576 GO:0005524 GO:0070733 GO:0048365 GO:0006464 GO:0034259 GO:0035024 GO:0009405 GO:0018178 GO:0018117 GO:0043088 GO:0044054 | |
| InterPro | IPR003812 | |
| Pfam | PF02661 | |
| SUPFAM | SSF140931 | |
| PROSITE | PS51459 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0048365 |
Rac GTPase binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0044054 |
rounding by symbiont of host cells |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0043087 |
regulation of GTPase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0035024 |
negative regulation of Rho protein signal transduction |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0018178 |
peptidyl-threonine adenylylation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0070733 |
protein adenylyltransferase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0070733 |
protein adenylyltransferase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0034260 |
negative regulation of GTPase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0018117 |
protein adenylylation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009405 |
pathogenesis |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006464 |
cellular protein modification process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016779 |
nucleotidyltransferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009405 |
pathogenesis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Yarbrough, ML et al. (2009) AMPylation of Rho GTPases by Vibrio VopS disrupts effector binding and downstream signaling. Science 323 269-72 PubMed GONUTS page
- ↑ 2.0 2.1 Luong, P et al. (2010) Kinetic and structural insights into the mechanism of AMPylation by VopS Fic domain. J. Biol. Chem. 285 20155-63 PubMed GONUTS page
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