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VIBHA:A6AR68
Contents
| Species (Taxon ID) | Vibrio harveyi HY01. (410291) | |
| Gene Name(s) | No Information Provided. | |
| Protein Name(s) | Histone deacetylase/AcuC/AphA family protein | |
| External Links | ||
| UniProt | A6AR68 | |
| EMBL | AAWP01000025 | |
| ProteinModelPortal | A6AR68 | |
| EnsemblBacteria | EDL68769 | |
| PATRIC | 31189960 | |
| Gene3D | 3.40.800.20 | |
| InterPro | IPR000286 IPR023801 | |
| PANTHER | PTHR10625 | |
| Pfam | PF00850 | |
| PRINTS | PR01270 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0010944 |
negative regulation of transcription by competitive promoter binding |
IMP: Inferred from Mutant Phenotype |
P |
AphA is shown to negatively regulate the expression of genes qrr2, qrr3 and qrr4 in figure 2B when an aphA deletion causes an increase in expression of qrr2,3 and 4. It also shows negative regulation of qrr4 in figure 2A when an aphA interrupted mutant resulted in an increase in qrr4 expression. Further in the paper, figure 3 shows that AphA binds directly to the qrr4 promoter negatively regulating transcription. |
complete | |||
| GO:0052097 |
interspecies quorum sensing |
IGI: Inferred from Genetic Interaction |
|
P |
Figure 2 shows that LuxR and AphA have assymetrical production profiles |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Rutherford, ST et al. (2011) AphA and LuxR/HapR reciprocally control quorum sensing in vibrios. Genes Dev. 25 397-408 PubMed GONUTS page
- ↑ van Kessel, JC et al. (2013) Individual and combined roles of the master regulators AphA and LuxR in control of the Vibrio harveyi quorum-sensing regulon. J. Bacteriol. 195 436-43 PubMed GONUTS page
