VIBF1:Q5E593

Species (Taxon ID)	Vibrio fischeri (strain ATCC 700601 / ES114). (312309)
Gene Name(s)	fnr (ECO:0000313 with EMBL:AAW85803.2)
Protein Name(s)	Transcriptional regulatory protein Fnr, global regulator of anaerobic growth (ECO:0000313 with EMBL:AAW85803.2)
External Links
UniProt	Q5E593
EMBL	CP000020
RefSeq	YP_204691.2
ProteinModelPortal	Q5E593
STRING	312309.VF_1308
EnsemblBacteria	AAW85803
GeneID	3278638
KEGG	vfi:VF_1308
PATRIC	20113232
eggNOG	COG0664
HOGENOM	HOG000186461
KO	K01420
OMA	AIRTGFF
OrthoDB	EOG6RVFWF
BioCyc	AFIS312309:GIWP-1370-MONOMER
Proteomes	UP000000537
GO	GO:0005622 GO:0003677 GO:0003700 GO:0009061 GO:0071454 GO:0045892 GO:0045893 GO:0006351
Gene3D	1.10.10.10 2.60.120.10
InterPro	IPR018490 IPR000595 IPR012318 IPR014710 IPR001808 IPR018335 IPR011991
Pfam	PF00027
PRINTS	PR00034
SMART	SM00100 SM00419
SUPFAM	SSF51206
PROSITE	PS50042 PS00042 PS51063

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0009061	anaerobic respiration	PMID:20298504	ECO:0000315			P		Fig. 1c, V. fischeri fnr mutants do not grow in minimal medium under anaerobic conditions.	complete
	GO:0008940	nitrate reductase activity	PMID:20298504	ECO:0000315			F		Fig. 1c, V. fischeri fnr mutants displayed nitrate-or fumarate-dependent growth in minimal medium under anaerobic conditions.	complete
	GO:0016156	fumarate reductase (NADH) activity	PMID:20298504	ECO:0000315			F		Fig. 1c, V. fischeri fnr mutants displayed nitrate-or fumarate-dependent growth in minimal medium under anaerobic conditions.	complete
	GO:0008218	bioluminescence	PMID:20298504	ECO:0000315			P		Fig. 2a, the luminescence of the fnr mutants was similar to that of their parent strains under aerobic conditions.	complete
	GO:0047646	alkanal monooxygenase (FMN-linked) activity	PMID:20298504	ECO:0000315			F		Fig. 2b, the fnr mutant EVS601 gives off luminescence when grown anaerobically.	complete
	GO:0071454	cellular response to anoxia	PMID:20298504	ECO:0000315			P		Fig. 2b, when grown anaerobically, luminescence was higher in fnr mutant EVS601 than in MJ1.	complete
	GO:0010628	positive regulation of gene expression	PMID:20298504	ECO:0000315			P		Fig. 2c, autoinducer 3-oxo-C6-HSL stimulated the luminescence of ES114 and JB1, and under these conditions fnr mutant JB1 was brighter than ES114.	complete
	GO:0016563	transcription activator activity	PMID:20298504	ECO:0000315			F		Fig. 3, fnr was responsible for about 2-4 fold activation of the arcA promoter(s) anaerobically in ES114 and MJ1 backgrounds.	complete
	GO:0016566	specific transcriptional repressor activity	PMID:20298504	ECO:0000315			F		Fig. 2c indicate that the fnr mutant was significantly brighter than the corresponding isogenic fnr-positive strain under anaerobic growth conditions.	complete
	GO:0016455	RNA polymerase II transcription mediator activity	PMID:20298504	ECO:0000315			F		Fig. 3, arcA-lacZ reporters showed a lower expression in the absence of fnr.	complete
involved_in	GO:0071454	cellular response to anoxia	PMID:20298504	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:20298504	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	PMID:20298504	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0009061	anaerobic respiration	PMID:20298504	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012318	F		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR018335	F		Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012318 InterPro:IPR018335	P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
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References

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