VIBCL:Q9ZH73

Species (Taxon ID)	Vibrio cholerae. (666)
Gene Name(s)	varA (ECO:0000313 with EMBL:AAC82663.1)
Protein Name(s)	GacA-like protein (ECO:0000313 with EMBL:AAC82663.1)
External Links
UniProt	Q9ZH73
EMBL	AF071105
ProteinModelPortal	Q9ZH73
STRING	345073.VC395_1332
eggNOG	ENOG4105WH1 COG2197
GO	GO:0005622 GO:0003677 GO:0009405 GO:0000160 GO:0006355 GO:0006351
Gene3D	1.10.10.10
InterPro	IPR011006 IPR016032 IPR001789 IPR000792 IPR011991
Pfam	PF00196 PF00072
PRINTS	PR00038
SMART	SM00421 SM00448
SUPFAM	SSF46894 SSF52172
PROSITE	PS00622 PS50043 PS50110

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0009405	pathogenesis	PMID:9826365	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0000160	phosphorelay signal transduction system	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001789	P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016032	F		Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000792 InterPro:IPR016032	P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
	GO:0009405	pathogenesis	PMID:9826365	ECO:0000315			P		Table 2 shows the varA deficient mutant has reduced expression of cholera toxin when compared to wild type, and varA mutant reverted to wild type. Additionally, Table 4 shows that varA mutants have a lower competitive index in mice colonization.	complete CACAO 2177
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References

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