User:Mmohieddin

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
unacceptable	RABIT:A9Z0W1	2016-04-15 12:32:39 CDT	GO:0071735 IgG immunoglobulin complex (C)	PMID:3256154	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 8 shows that when FcRn is overexpressed the IgG complex has a longer half-life	challenge
unacceptable	RABIT:A9Z0W1	2016-04-15 12:32:40 CDT	GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin (P)	PMID:3256154	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 9 shows that overexpression of rabbit FcRn results in an augmented humoral immune response in transgenic rabbits.	challenge
acceptable	RHOCB:SENC	2016-04-12 02:24:45 CDT	GO:1904960 positive regulation of cytochrome-c oxidase activity (P)	PMID:7592491	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 4 shows a qualitative analysis of the effect of SenC mutation on cytochrome-c oxidase activity. Based on the figure, It was concluded that senC mutations exhibit greatly reduced, but not entirely absent, Cox activity.	challenge
unacceptable	RHOCB:SENC	2016-04-12 03:04:31 CDT	GO:0009765 photosynthesis, light harvesting (P)	PMID:7592491	ECO:0000315 mutant phenotype evidence used in manual assertion	Figures 5 and 6 show that mutation in senC results in reduced levels of light-harvesting bacteriochlorophyll complexes.	challenge
acceptable	ECOLI:SSNA	2016-04-19 09:43:28 CDT	GO:0030308 negative regulation of cell growth (P)	PMID:10074077	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 1 shows the negative effect of the ssnA on cell growth.	challenge
updatedbyinstructor	ARATH:GCA2	2016-04-19 02:35:40 CDT	GO:0005747 mitochondrial respiratory chain complex I (C)	PMID:26889912	ECO:0000314 direct assay evidence used in manual assertion	Figure 1d	challenge
unacceptable	ARATH:GCA2	2016-04-19 02:43:36 CDT	GO:2000375 negative regulation of oxygen metabolic process (P)	PMID:26889912	ECO:0000316 genetic interaction evidence used in manual assertion	Figure 5 shows that a double mutation in CA1 and CA2 result in increased oxygen consumption.	challenge
unacceptable	ARATH:GCA2	2016-04-19 02:48:09 CDT	GO:1904959 regulation of cytochrome-c oxidase activity (P)	PMID:26889912	ECO:0000316 genetic interaction evidence used in manual assertion	Figure 4d shows that a double mutation in ca1 and ca2 drastically increase cytochrome-c oxidase activity. This suggests that ca2 along with ca1 negatively regulates cytochrome-c oxidase activity	challenge
unacceptable	ARATH:GCA1	2016-04-19 02:53:14 CDT	GO:2000375 negative regulation of oxygen metabolic process (P)	PMID:26889912	ECO:0000316 genetic interaction evidence used in manual assertion	Figure 5 shows that a double mutation in ca1 and ca2 increases energy consumption. This suggests that ca1 negatively regulate oxygen consumption.	challenge
unacceptable	ARATH:GCA1	2016-04-19 03:05:32 CDT	GO:1904959 regulation of cytochrome-c oxidase activity (P)	PMID:26889912	ECO:0000316 genetic interaction evidence used in manual assertion	Figure 4d shows that when a double mutation in ca1 and ca2 occurs, cytochrome-c oxidase activity increases drastically. Thus, the data suggests that ca1 negatively regulates cytochrome-c oxidase activity	challenge

acceptable:2
unacceptable:7
requires_changes:0
flagged:0

Annotations challenged by Mmohieddin

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history

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