User:Cwarden

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
unacceptable	XENTR:Q0IHV4	2014-02-02 16:46:36 CST	GO:0050321 tau-protein kinase activity (F)	PMID:1376245	ECO:0000314 direct assay evidence used in manual assertion	Figure 1 shows that p34-cycB is not likely to be responsible for the transformation of tau.	challenge
unacceptable	XENTR:Q0IHV4	2014-02-02 16:51:28 CST	GO:0050321 tau-protein kinase activity (F)	PMID:1376245	ECO:0000314 direct assay evidence used in manual assertion	Figure 2 shows that the effects of the MAP kinases were indistinguishable from the brain extract, suggesting that a similar enzyme was dominant in the extract	challenge
unacceptable	XENTR:Q0IHV4	2014-02-02 17:18:10 CST	GO:0050321 tau-protein kinase activity (F)	PMID:1376245	ECO:0000314 direct assay evidence used in manual assertion	Figure 3 further confirmed that a MAP kinase was present in brain extract that led to a phosphorylation of tyrosine, which confirmed it was present in the brain extract	challenge
unacceptable	XENTR:Q0IHV4	2014-02-02 17:55:32 CST	GO:0050321 tau-protein kinase activity (F)	PMID:1376245	ECO:0000314 direct assay evidence used in manual assertion	Figure 7 shows that the time course of phorphorylation of tau with MAP kinase is similar to the results obtained with the brain extract, except the results increased significantly with purification	challenge
unacceptable	XENTR:Q0IHV4	2014-02-02 17:57:50 CST	GO:0050321 tau-protein kinase activity (F)	PMID:1376245	ECO:0000314 direct assay evidence used in manual assertion	Figure 8 shows that the effect of MAP kinase can also be demonstrated directly with PHF tau from an Alzheimer brain.	challenge

acceptable:0
unacceptable:5
requires_changes:0
flagged:0

Annotations challenged by Cwarden

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history

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