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User:Burtontr2

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Phage Hunters Spring 2017

My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
flaggedCANAX:DYR2017-04-16 16:27:18 CDTGO:0004146 dihydrofolate reductase activity (F)PMID:9374515ECO:0000247 sequence alignment evidence used in manual assertion

The HHpred predicted E-value for this is 1.2E-32. In the literature Fig. 1 compares Candida albicans' Dihydrofolate Reductase to Pneumocystis carinii and they share a 34% match with each other's amino acid sequence. The activity also matches the yeast gene DFR1.

challenge
9CAUD:Q8LTE62017-04-30 22:59:06 CDTGO:0009253 peptidoglycan catabolic process (P)PMID:28414782ECO:0000317 genomic context evidence used in manual assertion

The HHpred E-value is 3.5E^-25. The daughter cells in the paper require peptidoglycan catabolic process to separate. A fractured cell wall released lysosome and mutanolysin digestion. This related in the long amino acid chains breaking apart.

challenge

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unacceptable:0
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Annotations challenged by Burtontr2

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