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UROYA:KAX6L
Contents
Species (Taxon ID) | Urodacus yaschenkoi (Inland robust scorpion). (1273102) | |
Gene Name(s) | No Information Provided. | |
Protein Name(s) | Potassium channel toxin alpha-KTx 6.21
Urotoxin | |
External Links | ||
UniProt | P0DL37 | |
GO | GO:0005576 GO:0008200 GO:0006952 GO:0009405 | |
Gene3D | 3.30.30.10 | |
InterPro | IPR003614 IPR001947 | |
Pfam | PF00451 | |
PRINTS | PR00286 | |
ProDom | PD003586 | |
SUPFAM | SSF57095 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0044361 |
envenomation resulting in modulation of transmission of nerve impulse in other organism |
ECO:0000314 |
P |
Figure 5 shows the inhibition of current through the hKv1.1 channel by purified urotoxin. Figure 5, panel B shows the dose-dependent manner of inhibition. Figure 5 panel C shows that this is reversible and current is restored after urotoxin is no longer applied. |
complete | |||||
part_of |
GO:0005576 |
extracellular region |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0008200 |
ion channel inhibitor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0009405 |
pathogenesis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0090729 |
toxin activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Luna-Ramírez, K et al. (2014) Structure, molecular modeling, and function of the novel potassium channel blocker urotoxin isolated from the venom of the Australian scorpion Urodacus yaschenkoi. Mol. Pharmacol. 86 28-41 PubMed GONUTS page
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