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TRYB2:Q4GZ50
Contents
| Species (Taxon ID) | Trypanosoma brucei brucei (strain 927/4 GUTat10.1). (185431) | |
| Gene Name(s) | KREPB1 (ECO:0000313 with EMBL:CAJ16173.1) | |
| Protein Name(s) | RNA-editing complex protein nuclease, putative KREPB1 (ECO:0000313 with EMBL:CAJ16173.1) | |
| External Links | ||
| UniProt | Q4GZ50 | |
| EMBL | AL929603 | |
| RefSeq | XP_001218871.1 | |
| ProteinModelPortal | Q4GZ50 | |
| STRING | 5691.Tb927.1.1690 | |
| GeneID | 4357244 | |
| KEGG | tbr:Tb927.1.1690 | |
| eggNOG | NOG137030 | |
| InParanoid | Q4GZ50 | |
| OMA | AFERLEY | |
| Proteomes | UP000008524 | |
| GO | GO:0045293 GO:0004518 GO:0004525 GO:0003723 GO:0008270 GO:0016556 GO:0090305 GO:0006396 | |
| Gene3D | 1.10.1520.10 | |
| InterPro | IPR000999 | |
| SUPFAM | SSF69065 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0004525 |
ribonuclease III activity |
ECO:0000314 |
F |
Figure 4 shows U-deletion cleavage activity of rTbMP90 (also known as KREPB1). Deletion of this is used, mutating the trypanosomes and changing the phenotype as a result. |
complete | |||||
|
enables |
GO:0004525 |
ribonuclease III activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0045293 |
mRNA editing complex |
ECO:0000353 |
physical interaction evidence used in manual assertion |
GeneDB:Tb927.9.4360 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0031019 |
mitochondrial mRNA editing complex |
ECO:0000245 |
automatically integrated combinatorial evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031019 |
mitochondrial mRNA editing complex |
ECO:0000245 |
automatically integrated combinatorial evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031019 |
mitochondrial mRNA editing complex |
ECO:0000245 |
automatically integrated combinatorial evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031019 |
mitochondrial mRNA editing complex |
ECO:0000245 |
automatically integrated combinatorial evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016556 |
mRNA modification |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000245 |
automatically integrated combinatorial evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000245 |
automatically integrated combinatorial evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000245 |
automatically integrated combinatorial evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000245 |
automatically integrated combinatorial evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004521 |
endoribonuclease activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0004518 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0090501 |
RNA phosphodiester bond hydrolysis |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004525 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0090501 |
RNA phosphodiester bond hydrolysis |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0004525 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0090502 |
RNA phosphodiester bond hydrolysis, endonucleolytic |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004525 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0090502 |
RNA phosphodiester bond hydrolysis, endonucleolytic |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0004525 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0090502 |
RNA phosphodiester bond hydrolysis, endonucleolytic |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0004521 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004525 |
ribonuclease III activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006396 |
RNA processing |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016556 |
mRNA modification |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008270 |
zinc ion binding |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004518 |
nuclease activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Kang, X et al. (2006) Reconstitution of full-round uridine-deletion RNA editing with three recombinant proteins. Proc. Natl. Acad. Sci. U.S.A. 103 13944-9 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Panigrahi, AK et al. (2003) Identification of novel components of Trypanosoma brucei editosomes. RNA 9 484-92 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Gazestani, VH et al. (2016) A Protein Complex Map of Trypanosoma brucei. PLoS Negl Trop Dis 10 e0004533 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Zhang, X et al. (2010) The Trypanosoma brucei MitoCarta and its regulation and splicing pattern during development. Nucleic Acids Res. 38 7378-87 PubMed GONUTS page
- ↑ Panigrahi, AK et al. (2006) Compositionally and functionally distinct editosomes in Trypanosoma brucei. RNA 12 1038-49 PubMed GONUTS page
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