THET2:SODM

Species (Taxon ID)	Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039). (262724)
Gene Name(s)	sodA
Protein Name(s)	Superoxide dismutase [Mn]
External Links
UniProt	P61502
EMBL	AB010884 AE017221
PIR	T43728
RefSeq	WP_011172643.1
ProteinModelPortal	P61502
SMR	P61502
STRING	262724.TT_C0189
EnsemblBacteria	AAS80537
KEGG	tth:TT_C0189
eggNOG	ENOG4105CK4 COG0605
KO	K04564
OMA	KWGSFDK
OrthoDB	1440645at2
Proteomes	UP000000592
GO	GO:0046872 GO:0004784
Gene3D	1.10.287.990 2.40.500.20
InterPro	IPR001189 IPR019833 IPR019832 IPR019831 IPR036324 IPR036314
Pfam	PF02777 PF00081
PIRSF	PIRSF000349
PRINTS	PR01703
SUPFAM	SSF46609 SSF54719
PROSITE	PS00088

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0019430	removal of superoxide radicals	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004784	P		Seeded From UniProt
involved_in	GO:0019430	removal of superoxide radicals	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004784	P		Seeded From UniProt
enables	GO:0004784	superoxide dismutase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001189 InterPro:IPR019831 InterPro:IPR019832 InterPro:IPR019833	F		Seeded From UniProt
involved_in	GO:0006801	superoxide metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001189 InterPro:IPR019831 InterPro:IPR019832 InterPro:IPR019833	P		Seeded From UniProt
enables	GO:0046872	metal ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001189 InterPro:IPR019831 InterPro:IPR019832 InterPro:IPR019833	F		Seeded From UniProt
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001189 InterPro:IPR019831 InterPro:IPR019832 InterPro:IPR019833	P		Seeded From UniProt
enables	GO:0004784	superoxide dismutase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:1.15.1.1	F		Seeded From UniProt
enables	GO:0016491	oxidoreductase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	F		Seeded From UniProt
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	P		Seeded From UniProt
involved_in	GO:0019430	removal of superoxide radicals	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004784	P		Seeded From UniProt
involved_in	GO:0019430	removal of superoxide radicals	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004784	P		Seeded From UniProt
enables	GO:0004784	superoxide dismutase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001189 InterPro:IPR019831 InterPro:IPR019832 InterPro:IPR019833	F		Seeded From UniProt
involved_in	GO:0006801	superoxide metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001189 InterPro:IPR019831 InterPro:IPR019832 InterPro:IPR019833	P		Seeded From UniProt
enables	GO:0046872	metal ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001189 InterPro:IPR019831 InterPro:IPR019832 InterPro:IPR019833	F		Seeded From UniProt
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001189 InterPro:IPR019831 InterPro:IPR019832 InterPro:IPR019833	P		Seeded From UniProt
enables	GO:0004784	superoxide dismutase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:1.15.1.1	F		Seeded From UniProt
enables	GO:0016491	oxidoreductase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	F		Seeded From UniProt
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	P		Seeded From UniProt
	GO:0071793	bacillithiol biosynthetic process	PMID:30940703	ECO:0001272	high-performance liquid chromatography evidence used in manual assertion		P		In Δsod Thermus thermophilus mutants, HPLC is used to observe a statistically significant drop in reduced bacillthiol pools (BSH), despite the total BSH (oxidized and reduced) concentrations remaining the same. Sod (superoxide dismutase) is a well-characterized antioxidant enzyme and its deletion, combined with the difference in reduced BSH levels, suggests Sod plays a role in BSH oxidation.	complete CACAO 13753
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References

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