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THEMA:MTAD

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Species (Taxon ID) Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099). (243274)
Gene Name(s) mtaD
Protein Name(s) 5-methylthioadenosine/S-adenosylhomocysteine deaminase

MTA/SAH deaminase

External Links
UniProt Q9X034
EMBL AE000512
PIR H72315
RefSeq NP_228744.1
YP_007977288.1
YP_008991965.1
PDB 1J6P
1P1M
2PLM
PDBsum 1J6P
1P1M
2PLM
ProteinModelPortal Q9X034
SMR Q9X034
STRING 243274.TM0936
ChEMBL CHEMBL1075031
EnsemblBacteria AAD36017
GeneID 18093779
898610
KEGG tma:TM0936
PATRIC 23936803
eggNOG COG0402
InParanoid Q9X034
KO K12960
OMA HEEWIAK
OrthoDB EOG65QWFB
BioCyc MetaCyc:MONOMER-16147
EvolutionaryTrace Q9X034
Proteomes UP000008183
GO GO:0046872
GO:0050270
Gene3D 2.30.40.10
HAMAP MF_01281
InterPro IPR006680
IPR023512
IPR011059
Pfam PF01979
SUPFAM SSF51338

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0050270

S-adenosylhomocysteine deaminase activity

PMID:23968233[1]

ECO:0000314

F

Table 1, row m, kcat/Km value for SAH

complete
CACAO 10167

enables

GO:0050270

S-adenosylhomocysteine deaminase activity

PMID:23968233[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0050270

S-adenosylhomocysteine deaminase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001681698
UniProtKB:Q9X034

F

Seeded From UniProt

complete

enables

GO:0004000

adenosine deaminase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001681698
UniProtKB:Q81F14
UniProtKB:Q9HZ64

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006680

F

Seeded From UniProt

complete

enables

GO:0016810

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011059

F

Seeded From UniProt

complete

enables

GO:0019239

deaminase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR023512

F

Seeded From UniProt

complete

enables

GO:0050270

S-adenosylhomocysteine deaminase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.5.4.28

F

Seeded From UniProt

complete

enables

GO:0050270

S-adenosylhomocysteine deaminase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000101653

F

Seeded From UniProt

complete

enables

GO:0090614

5'-methylthioadenosine deaminase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000101653

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Hitchcock, DS et al. (2013) Structure-guided discovery of new deaminase enzymes. J. Am. Chem. Soc. 135 13927-33 PubMed GONUTS page
  2. 2.0 2.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page