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TAXBR:TASY

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Species (Taxon ID) Taxus brevifolia (Pacific yew). (46220)
Gene Name(s) TDC1
Protein Name(s) Taxadiene synthase

Taxa-4(5),11(12)-diene synthase

External Links
UniProt Q41594
EMBL U48796
AF326519
PDB 3P5P
3P5R
PDBsum 3P5P
3P5R
ProteinModelPortal Q41594
BioCyc MetaCyc:MONOMER-13385
UniPathway UPA00842
EvolutionaryTrace Q41594
GO GO:0000287
GO:0050553
GO:0010333
GO:0042617
Gene3D 1.10.600.10
1.50.10.20
1.50.30.10
InterPro IPR001906
IPR005630
IPR008930
IPR008949
Pfam PF01397
PF03936
SUPFAM SSF48239
SSF48576

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0050553

taxadiene synthase activity

PMID:757471[1]

ECO:0000314

F

Figure 2: In vitro test of Mg2+ concentration on taxadiene synthase activity. Shows increased taxadiene formation with increased Mg2+.

complete

enables

GO:0000287

magnesium ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005630

F

Seeded From UniProt

complete

enables

GO:0010333

terpene synthase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001906
InterPro:IPR005630
InterPro:IPR036965

F

Seeded From UniProt

complete

enables

GO:0016829

lyase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001906
InterPro:IPR005630
InterPro:IPR036965

F

Seeded From UniProt

complete

enables

GO:0050553

taxadiene synthase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:4.2.3.17

F

Seeded From UniProt

complete

involved_in

GO:0042617

paclitaxel biosynthetic process

GO_REF:0000037
GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0876
UniPathway:UPA00842

P

Seeded From UniProt

complete

enables

GO:0016829

lyase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0456

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. De Palma, L & Di Lazzaro, A (1978) [Clinical and pathogenetic observations on the lumbar herniated disk syndrome in the aged]. Arch Putti Chir Organi Mov 29 139-47 PubMed GONUTS page