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Cacao
| GO:2000147 | positive regulation of cell motility | PMID:22804504 | IGI: Inferred from Genetic Interaction UniProtKB: Q95604 | P | ||||
| This annotation made on page: HUMAN:WASP By: Marisagee (group Team BTHO Annotations) on 2012-11-13 12:30:40 CST. | ||||||||
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| Entry Type | Challenging User,Group | Time/Date | Challenge Reason | Points/Assessment |
|---|---|---|---|---|
| Challenge | Marisagee, Team BTHO Annotations | 2012-11-20 20:05:56 CST | The correct term should be GO:2000146, negative regulation of cell motility, that is correct. However, a JY cell is a HLA class 1, as shown in the "synonyms". Fig 2a shows that in the presence of JY cells the motility of WASP deficient T-cells is significantly increased. | 1 |
| Challenge | Cbice1, Team Smarter Who? | 2012-11-18 18:15:56 CST | This figure shows that when WASP is knocked down by shRNA, cells migrate more. This would suggest that WASP is negatively regulating motility, not positively regulating it. Additionally, I don’t think IGI is the right evidence code, as this figure doesn’t even mention the protein in the with/from field here. | 1 |
| Private Assessment | Suzialeksander | 2013-06-24 11:09:24 CDT | You need to be an instructor to view these notes. | Updated by Instructor ✔ Protein ✔ Publication ✔ Qualifier ✔ Go term ✔ Evidence ✔ With/From ✔ Notes ✔ Unique/Original |
| Private Assessment | Bmcintosh | 2012-11-28 10:07:05 CST | You need to be an instructor to view these notes. | Requires Changes |
