GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
Cacao
| GO:0032891 | negative regulation of organic acid transport | PMID:22837003 | IMP: Inferred from Mutant Phenotype | P | ||||
| This annotation made on page: MOUSE:ACE2 By: Nfarmer91 (group Team BTHO Annotations) on 2012-10-30 20:37:04 CDT. | ||||||||
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| Entry Type | Challenging User,Group | Time/Date | Challenge Reason | Points/Assessment |
|---|---|---|---|---|
| Challenge | Cbice1, Team Smarter Who? | 2012-11-06 20:23:59 CST | The figures cited (2d-f and S16) use tryptophan, which is definitely an amino acid. So "amino acid" GO terms would be more specific than "organic acid" and would be correct. However, better still might be "regulation of dipeptide transport" since in the text they say they supply Trp as a dipeptide. I suppose there is some question of whether these figures do show "transport" of the didpeptide. I think figure S16a shows "amino acid homeostasis" at least. | 0 |
| Challenge | Romero.alan, Team BTHO Annotations | 2012-11-06 15:46:38 CST | I disagree, I beleive there is enough evidence to make that conclusion. However i disagree with both of you in finding the appropriate go term. I beleive the appropriate go term should just be regulation of organic acid transport. | 0 |
| Challenge | Cbice1, Team Smarter Who? | 2012-11-04 21:22:40 CST | The fact that a deficiency of Ace2 causes impairment of trp homeostasis isn't enough evidnece to conclude that Ace is a negative regulator of organic acid transport. I think "regulation of amino acid transport" is a better GO term. | 1 |
| Private Assessment | Suzialeksander | 2013-06-24 11:12:31 CDT | You need to be an instructor to view these notes. | Acceptable ✔ Protein ✔ Publication ✔ Qualifier ✔ Go term ✔ Evidence ✔ With/From ✔ Notes ✔ Unique/Original |
| Private Assessment | Bmcintosh | 2012-11-09 09:46:14 CST | You need to be an instructor to view these notes. | Requires Changes |
