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The row for this annotation cannot be found. This might be due to a row or page getting deleted.

GO:2000969positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activityPMID:20869594ISA: Inferred from Sequence Alignment UniProtKB:D2X2K4 P
This annotation made on page:
By: Sejal (group Team UCL-Maple Leafs) on 2011-11-20 16:35:31 CST.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeSejal,
Team UCL-Maple Leafs
2011-11-22 14:35:44 CST

I am not sure what you mean. The experimental evidence in the paper uses the xenopus Nlgn1 protein. However in figure1A the xenopus protein sequence is compared against other mammals that have similar sequence domains. Therefore the GO terms annotated to xenopus can be annotated to the other species seen in figure 1A based on sequence alignment.

Also the sequence alignment are orthologs of Nlgn1 between other species that are being compared to the xenopus Nlgn1 protein sequence.

0
ChallengeNrache1,
Team Polymerase Chain Re-awesome
2011-11-21 20:07:22 CST

The annotation is valid, but the same protein was used multiple times with different GO terms.

0
Private
Assessment
Sgouni2011-11-22 16:24:27 CSTYou need to be an instructor to view these notes.Acceptable