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Cacao

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GO:0016342catenin complexPMID:7806582IDA: Inferred from Direct Assay C
This annotation made on page: HUMAN:APC
By: Caroline.smith.10 (group Team UCL-Maple Leafs) on 2011-11-16 13:16:06 CST.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeSejal,
Team UCL-Maple Leafs
2011-11-21 15:53:33 CST

The GO term: GO:0016342 catenin complex is cellular component term therefore the evidence given shows that APC is part of catenin complex (being linked to beta catenin) Therefore this GO term is not meant to show localization of the protein which is a biological process. The new GO term you suggested (Team That Will Beat You) is a biological process term and it seem like a valid GO term to use but the immunoprecipitation experiment does not show the assembly (aggregation, arrangement)of component to form the complex, the only thing that is shown is the bonding.

0
ChallengeOherrera,
Team That Will Beat You!!!
2011-11-20 18:04:58 CST

The evidence provided does not show localization of the protein to the catenin complex but rather the formation of the complex. I think the GO term should be GO:0006461 - Protein Complex Assembly.

0
Public
Assessment
Bmcintosh2011-11-22 14:44:58 CST

I agree with the original annotation.

Acceptable