GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
Cacao
| GO:0045449 | regulation of transcription | PMID:12923093 | IMP: Inferred from Mutant Phenotype | 1 | ||||
| This annotation made on page: By: Nkogekar (group Team Slithytoads) on 2011-10-21 18:54:45 CDT. | ||||||||
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| Entry Type | Challenging User,Group | Time/Date | Challenge Reason | Points/Assessment |
|---|---|---|---|---|
| Challenge | Nkogekar, Team Slithytoads | 2011-11-13 12:26:07 CST | This is a rebuttal to Mdao3's challenge: It is true that in the text they say that the FAr conferring mutation (which was later found to be a mutation in the regulatory region of ydhL, or pbuE) affected gene expression, but in the experiments showing this, they employed lacZ fusions, which are really measuring the amount of transcription. So, this child-term seemed more fitting to me, as the evidence specifically shows a difference in the amount of transcription. | 0 |
| Challenge | Mdao3, Team That Will Beat You!!! | 2011-11-08 20:02:39 CST | better GO term, from text, "The FAr-conferring mutation clearly had a trans-acting effect since it affected gene expression at three different loci on the chromosome (Table (Table2).2)." | 0 |
| Public Assessment | Davidmigl | 2011-11-15 20:39:59 CST | Both teams are missing the point here. pbuE is a purine efflux pump and has nothing to do with gene regulation. It is the expression of pbuE that is being regulated here. The paper seems to be more about RNA secondary structure and its role in regulation of the pur operon. | Unacceptable |
