GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
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Cacao
| GO:1990001 | inhibition of cysteine-type endopeptidase activity involved in apoptotic process | PMID:27911947 | ECO:0007183 | Biological Process | Figure 2D shows Western Blot data showing decreased pro-Caspase-1 and IL-1B, the inactive form of Caspase-1 that plays a role in Pyrin Inflammasome activation and the inactive form of IL-1B that is activated by Caspase-1, respectively, in the YopM mutants. This is indicative of more activation of Caspase-1 and IL-1B in the absence of YopM, which implies increased Pyrin Inflammasome activation. The figure also shows increased IL-1B in the YopM mutant, which inversely corresponds with the IL-1B protein expression data. Yersinia pests | complete | ||
| This annotation made on page: YERPE:YOPM By: ADPowell (group Catalyzers) on 2019-04-09 16:16:56 CDT. | ||||||||
You must be logged in to challenge this annotation.
| Entry Type | Challenging User,Group | Time/Date | Challenge Reason | Points/Assessment |
|---|---|---|---|---|
| Private Assessment | Jrr | 2019-04-12 01:06:25 CDT | You need to be an instructor to view these notes. | Acceptable ✔ Protein ✔ Publication ✔ Qualifier ✔ Go term ✔ Evidence ✔ With/From ✔ Notes ✔ Unique/Original |
