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Cacao

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GO:0001907killing by symbiont of host cellsPMID:25246571IDA: Inferred from Direct Assay P
This annotation made on page: SHIFL:IPA7
By: JonathanMarcias (group Team SEAL Team Ricks) on 2017-11-12 13:29:47 CST.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
Private
Assessment
Sandyl 272017-11-21 11:56:07 CSTYou need to be an instructor to view these notes.Acceptable
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original
Public
Assessment
DanielRenfro2017-11-20 15:37:53 CST

This annotation has been flagged because it has been edited since last assessment

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0034055 positive regulation by symbiont of host defense-related programmed cell death PMID:25246571 IMP: Inferred from Mutant Phenotype P Organism: Shigella Flexneri

protein: IPAH7.8 (in paper name) IPA7-Uniprot FIg 2A: "Shigella-induced IpaH7.8-dependent cell death occurs via caspase-1 activation...and [showed] that cell death occurred in an IpaH7.8-dependent manner"||complete
CACAO 12994

on SHIFL:IPA7
Flagged
Private
Assessment
Suzialeksander2017-11-20 14:36:56 CSTYou need to be an instructor to view these notes.Requires Changes
Go term
Notes
Public
Assessment
DanielRenfro2017-11-19 13:04:08 CST

This annotation has been flagged because it has been edited since last assessment

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001907 killing by symbiont of host cells PMID:25246571 IMP: Inferred from Mutant Phenotype P Organism: Shigella Flexneri

protein: IPAH7.8 (in paper name) According to figure S2B, IPA7 is sufficient for "killing my symbiont of host cells" The assay looks at macrophage cell deaths in presence of wild type and delta IPA7 Shigella. The delta has appreciably fewer macrophage deaths than the wild type IPA7, showing that IPA7 is responsible for killing of host cells ||complete
CACAO 12994

on SHIFL:IPA7
Flagged
Private
Assessment
Suzialeksander2017-11-15 23:17:11 CSTYou need to be an instructor to view these notes.Requires Changes
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original