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Cacao

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GO:0030236anti-inflammatory responsePMID:23083102IDA: Inferred from Direct Assay P
This annotation made on page: SHIFL:IPA4
By: JonathanMarcias (group Team SEAL Team Ricks) on 2017-10-26 19:17:39 CDT.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
Private
Assessment
Suzialeksander2017-11-01 13:29:52 CDTYou need to be an instructor to view these notes.Acceptable
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original
Public
Assessment
DanielRenfro2017-11-01 00:12:38 CDT

This annotation has been flagged because it has been edited since last assessment

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0044074 negative regulation by symbiont of host translation PMID:23083102 IDA: Inferred from Direct Assay P organism: Shigella flexneri

Fig 5A shows that cells with IPA4 had less transcriptional activity of NF-κB. "IpaH4.5 inhibits the transcriptional activity of NF-κB. "||complete
CACAO 12965

on SHIFL:IPA4
Flagged
Private
Assessment
Suzialeksander2017-10-31 15:34:25 CDTYou need to be an instructor to view these notes.Requires Changes
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original
Public
Assessment
DanielRenfro2017-10-31 14:28:29 CDT

This annotation has been flagged because it has been edited since last assessment

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0052170 negative regulation by symbiont of host innate immune response PMID:23083102 IDA: Inferred from Direct Assay P organism: Shigella flexneri

Fig 5A shows that cells with IPA4 had less transcriptional activity of NF-κB, which is part of the inflammatory response of the host. This is a dosage based response with increasing levels of IPA4 yielding a stronger anti-inflammatory response.||complete
CACAO 12965

on SHIFL:IPA4
Flagged
Private
Assessment
Suzialeksander2017-10-31 13:27:28 CDTYou need to be an instructor to view these notes.Requires Changes
Go term
Private
Assessment
CSears2017-10-31 12:32:38 CDTYou need to be an instructor to view these notes.Requires Changes
Protein
Publication
Qualifier
Go term
Evidence