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GO:0001756somitogenesisPMID:25372603IMP: Inferred from Mutant Phenotype P
This annotation made on page: CHICK:Q9I9C5
By: DTatarak (group Team Rable Rable) on 2017-06-15 10:40:22 CDT.



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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeOneHuckFinn,
Team Rable Starkey
2017-06-15 15:49:11 CDT

Fig 4 illustrates an effect of IRX-1 and IRX-2 concurrent over expression, so we can't conclude that any of the effects are specifically caused by IRX-1.

"Our results indicate that the AraucanaRp causative mutation is one of two (or both) SNPs within the proximal regulatory region of IRX1 and IRX2. "The dual misexpression of IRX1 and IRX2 supports this co-regulation model in which the AraucanaRp phenotype results from a gain-of-function mutation in the regulatory region of the IRX1 and IRX2 genes. "

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