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Contributes toGO:0019028viral capsidPMID:23840063ISS: Inferred from Sequence Similarity UniProtKB:Q858G8 C
This annotation made on page: BPE15:Q858G8
By: Farooquenb (group Team .jpeg) on 2017-04-12 13:47:16 CDT.



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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
Public
Assessment
DanielRenfro2017-04-30 22:43:40 CDT

This annotation has been flagged because it has been edited since last assessment

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0019028 viral capsid PMID:23840063 ISS: Inferred from Sequence Similarity UniProtKB:P49861 C Figure S6 in the supporting information document shows the structural homologs of gp7. Gp7 is a protein subunit of the capsid of epsilon15. The overall structure of gp7 is similar to the canonical bacteriophage coat proteins in tailed dsDNA bacteriophage. When the gp7 model is compared to the gp5 of HK97, the two structures are remarkably very similar. The two structures are nearly identical for about the first 145 amino acids. However, a domain swap in gp7 creates a 55% structural similarity according to CLICK. The two structures have a topology score of 1.0 according to CLICK. Therefore, the high structural similarity between HK97 gp5 and e15 gp7, provides further validation of the gp7 model. The evolutionary lineage of the e15 phage shows a highly conserved structural folding as supported by gp5 of HK97. complete
CACAO 12605
on BPE15:Q858G8
Flagged
Public
Assessment
AAJohnson2017-04-26 08:55:05 CDT

I believe you don't need a qualifier. The "with" field should contain the uniprot ID of a protein from the figure that is similar in structure to the one you're annotating (Q858G8). Notes- Your notes need to be more specific to describe what a capsid fold looks like. How do you know when you look at that figure that those curly rainbowy pictures are capsid? It's probably best to pull in a reference for a well-established capsid protein that has been structurally characterized, and to use that in your notes to support this annotation. HK97 is the canonical fold for capsids, and you'll have to look that up. :)

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