GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

Cacao

Jump to: navigation, search
Colocalizes withGO:0048471perinuclear region of cytoplasmPMID:25825816IDA: Inferred from Direct Assay C
This annotation made on page: HUMAN:SNX5
By: CSears (group Team Girl, you trypsin) on 2017-02-15 11:44:37 CST.




You must be logged in to challenge this annotation.

Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeTheBockster,
Team Daytona Bronze Viper
2017-03-07 14:02:29 CST

There should be no qualifier. The correct Go Term is GO:1905719 (protein localization to perinuclear region of cytoplasm). This association between SNX5 and the aforementioned Go Term occurs after insulin treatment. Thus, localization to the perinuclear region of the cytoplasm apparently occurs in part due to the fact that insulin kickstarts the cell's metabolism. According to the article, "There was minimal colocalization of SNX5 and IR in the basal state; colocalization of SNX5 and IR in the perinuclear area increased after 15 and 30 minutes of insulin (100nM) treatment (Figure 1C)."

1
Private
Assessment
Suzialeksander2017-04-26 12:46:27 CDTYou need to be an instructor to view these notes.Acceptable
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original
Public
Assessment
DanielRenfro2017-03-21 14:16:59 CDT

This annotation has been flagged because it has been edited since last assessment

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0048471 perinuclear region of cytoplasm PMID:25825816 IDA: Inferred from Direct Assay C Figure 1C: In human renal proximal tubule cells, SNX5 colocalized with the insulin receptor in the perinuclear area complete
CACAO 12283
on HUMAN:SNX5
Flagged
Private
Assessment
JimHu2017-03-21 13:36:41 CDTYou need to be an instructor to view these notes.Requires Changes
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original
Public
Assessment
DanielRenfro2017-03-07 14:02:29 CST

This annotation has been flagged because it has been challenged since last assessment

Flagged
Private
Assessment
Suzialeksander2017-03-03 16:13:27 CSTYou need to be an instructor to view these notes.Requires Changes
Go term