GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
Cacao
| GO:1990264 | peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity | PMID:26063811 | IDA: Inferred from Direct Assay | P | ||||
| This annotation made on page: HUMAN:PTPRO By: CSears (group Team Girl, you trypsin) on 2017-02-14 13:53:28 CST. | ||||||||
You must be logged in to challenge this annotation.
| Entry Type | Challenging User,Group | Time/Date | Challenge Reason | Points/Assessment | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Challenge | CSears, Team Girl, you trypsin | 2017-03-29 10:22:56 CDT | Figure 2B and 2C: Ptpro dephosphorylates tyrosine 1146 in the activation loop of the insulin receptor (a member of the receptor protein tyrosine kinase superfamily) in HEK293T (human embryonic kidney) cells | 2 | ||||||||||||||||||
| Challenge | TheBockster, Team Daytona Bronze Viper | 2017-03-28 14:24:10 CDT | The GO term and the Figure used do not quite match correctly here. Specifically, this GO term requires that dephosphorylation be linked to the inactivation of protein kinase activity. While that is proven in this paper it is NOT proven by Figure 1, and is instead proven later in the paper. If the Figure used was changed, this specific GO term could be used. It would ALSO be acceptable to simply use a less specific GO term. I suggest doing the latter. Therefore, I propose that the GO term used for this annotation should be GO:0035335 (peptidyl-tyrosine dephosphorylation). Just to be safe, I would also like to note that the long name of the protein (according to UniProt) is Receptor-type tyrosine-protein phosphatase O and the corresponding organism is Homo sapiens. | 1 | ||||||||||||||||||
| Challenge | SarahCouv, Team Lily Whale | 2017-02-24 15:50:43 CST | The protein is incorrect. The correct protein is E9Q612 (PTPRO_MOUSE). | 1 | ||||||||||||||||||
| Private Assessment | Suzialeksander | 2017-04-25 05:03:02 CDT | You need to be an instructor to view these notes. | Unacceptable ✗ Unique/Original | ||||||||||||||||||
| Public Assessment | DanielRenfro | 2017-04-04 13:15:55 CDT | This annotation has been flagged because it has been edited since last assessment
| Flagged | ||||||||||||||||||
| Public Assessment | DanielRenfro | 2017-03-29 10:22:56 CDT | This annotation has been flagged because it has been challenged since last assessment | Flagged | ||||||||||||||||||
| Public Assessment | DanielRenfro | 2017-03-28 14:24:10 CDT | This annotation has been flagged because it has been challenged since last assessment | Flagged | ||||||||||||||||||
| Private Assessment | Suzialeksander | 2017-03-03 15:20:55 CST | You need to be an instructor to view these notes. | Requires Changes ✔ Publication ✔ Qualifier ✗ Go term ✔ Evidence ✔ With/From ✗ Notes | ||||||||||||||||||
| Public Assessment | DanielRenfro | 2017-02-24 15:50:43 CST | This annotation has been flagged because it has been challenged since last assessment | Flagged | ||||||||||||||||||
| Private Assessment | Sandyl 27 | 2017-02-23 12:38:50 CST | You need to be an instructor to view these notes. | Requires Changes ✗ Protein |
