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GO:0050840extracellular matrix bindingPMID:23798385IDA: Inferred from Direct Assay F
This annotation made on page: HUMAN:PGS2
By: Henke01 (group Team RumRod) on 2014-10-21 22:00:46 CDT.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeRoosheel,
Team Thoth
2014-11-25 12:22:11 CST

Better GO Term would be: GO:0010508: Positive regulation of autophagy

Notes: Figure 2

8
ChallengeRoosheel,
Team Thoth
2014-10-28 19:02:39 CDT

no binding terms allowed

0
Private
Assessment
Suzialeksander2014-12-17 15:46:15 CSTYou need to be an instructor to view these notes.Updated by Instructor
Private
Assessment
JimHu2014-11-26 09:08:56 CSTYou need to be an instructor to view these notes.Corrected Through Challenges
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original
Private
Assessment
JimHu2014-11-25 21:00:47 CSTYou need to be an instructor to view these notes.Corrected Through Challenges
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original
Public
Assessment
DanielRenfro2014-11-25 12:22:11 CST

This annotation has been flagged because it has been edited since last assessment ||GO:0050840||extracellular matrix binding||PMID:23798385||IDA: Inferred from Direct Assay||||F||Decorin- induced Peg3 promoted the expression of autophagic proteins such as Beclin-1. Figure 7 Peg3 is required for decorin-evoked expression of the autophagic genes Beclin 1 and LC3 in MDEC and HUVEC. decorin, by binding to VEGFR2, triggers a signaling cascade leading to induction of Class III PI3K and enhanced Peg3 stability and/or accumulation which in turn recruits Beclin 1, β-catenin, and LC3 to evoke autophagy. Decorin significantly stabilizes BECN1 and MAPLC3A mRNA, but not PEG3 mRNA, in HUVEC. ||complete

Flagged
Public
Assessment
Suzialeksander2014-10-30 13:19:15 CDT

Grr I already pointed this out, thanks...

Requires Changes
Public
Assessment
DanielRenfro2014-10-28 19:02:39 CDT

This annotation has been flagged because it has been edited since last assessment ||GO:0050840||extracellular matrix binding||PMID:23798385||IDA: Inferred from Direct Assay||||F||Decorin- induced Peg3 promoted the expression of autophagic proteins such as Beclin-1. Figure 7 Peg3 is required for decorin-evoked expression of the autophagic genes Beclin 1 and LC3 in MDEC and HUVEC. decorin, by binding to VEGFR2, triggers a signaling cascade leading to induction of Class III PI3K and enhanced Peg3 stability and/or accumulation which in turn recruits Beclin 1, β-catenin, and LC3 to evoke autophagy. Decorin significantly stabilizes BECN1 and MAPLC3A mRNA, but not PEG3 mRNA, in HUVEC. ||complete

Flagged
Private
Assessment
Suzialeksander2014-10-27 12:43:17 CDTYou need to be an instructor to view these notes.Requires Changes
Go term
Private
Assessment
Suzialeksander2014-10-24 12:35:43 CDTYou need to be an instructor to view these notes.Flagged