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STRR6:NANA

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Species (Taxon ID) Streptococcus pneumoniae (strain ATCC BAA-255 / R6). (171101)
Gene Name(s) nanA
Protein Name(s) Sialidase A

Neuraminidase A

External Links
UniProt P62576
EMBL AE007317
PIR G98063
RefSeq NP_359129.1
WP_010976603.1
PDB 2W20
3H71
3H72
3H73
PDBsum 2W20
3H71
3H72
3H73
ProteinModelPortal P62576
SMR P62576
STRING 171101.spr1536
CAZy CBM40
GH33
EnsemblBacteria AAL00340
GeneID 933902
KEGG spr:spr1536
PATRIC 19703087
eggNOG COG4409
HOGENOM HOG000284737
KO K01186
OMA GGPKREN
OrthoDB EOG61CM2G
BioCyc SPNE171101:GJC8-1550-MONOMER
EvolutionaryTrace P62576
Proteomes UP000000586
GO GO:0005618
GO:0005576
GO:0016020
GO:0052794
GO:0052795
GO:0052796
GO:0005975
Gene3D 2.120.10.10
2.60.120.200
InterPro IPR002860
IPR013320
IPR004124
IPR001791
IPR019931
IPR026856
IPR011040
IPR005877
PANTHER PTHR10628
Pfam PF02012
PF02973
PF04650
SMART SM00282
SUPFAM SSF49899
SSF50939
TIGRFAMs TIGR01167
TIGR01168
PROSITE PS50847

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0005518

collagen binding

PMID:20624274[1]

ECO:0000314

F

Table 1

complete

GO:0070051

fibrinogen binding

PMID:20624274[1]

ECO:0000314

F

Table 1

complete

part_of

GO:0043231

intracellular membrane-bounded organelle

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000066595
UniProtKB:Q99519

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000066595
ZFIN:ZDB-GENE-061103-511

C

Seeded From UniProt

complete

involved_in

GO:0009313

oligosaccharide catabolic process

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000066595
UniProtKB:Q8WWR8
UniProtKB:Q99519
UniProtKB:Q9UQ49
UniProtKB:Q9Y3R4

P

Seeded From UniProt

complete

involved_in

GO:0006689

ganglioside catabolic process

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000066595
UniProtKB:O97859
UniProtKB:Q8WWR8
UniProtKB:Q9UQ49
UniProtKB:Q9Y3R4

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000066595
RGD:3164

C

Seeded From UniProt

complete

enables

GO:0004308

exo-alpha-sialidase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2661364
MGI:MGI:97305
PANTHER:PTN000066595
RGD:3163
RGD:3164
UniProtKB:Q4WQS0
UniProtKB:Q8WWR8
UniProtKB:Q99519
UniProtKB:Q9UQ49
UniProtKB:Q9Y3R4
ZFIN:ZDB-GENE-040801-262

F

Seeded From UniProt

complete

enables

GO:0004308

exo-alpha-sialidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004124
InterPro:IPR026856

F

Seeded From UniProt

complete

involved_in

GO:0005975

carbohydrate metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004124

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005877

C

Seeded From UniProt

complete

enables

GO:0052795

exo-alpha-(2->6)-sialidase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.2.1.18

F

Seeded From UniProt

complete

enables

GO:0004308

exo-alpha-sialidase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.2.1.18

F

Seeded From UniProt

complete

enables

GO:0052794

exo-alpha-(2->3)-sialidase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.2.1.18

F

Seeded From UniProt

complete

enables

GO:0052796

exo-alpha-(2->8)-sialidase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.2.1.18

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

enables

GO:0016798

hydrolase activity, acting on glycosyl bonds

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0326

F

Seeded From UniProt

complete

part_of

GO:0005618

cell wall

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0134
UniProtKB-SubCell:SL-0041

C

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

involved_in

GO:0008152

metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0326

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Frolet, C et al. (2010) New adhesin functions of surface-exposed pneumococcal proteins. BMC Microbiol. 10 190 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page