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STRPY:SPEB

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Species (Taxon ID) Streptococcus pyogenes. (1314)
Gene Name(s) speB
Protein Name(s) Streptopain

Exotoxin type B SPE B Streptococcal cysteine proteinase Streptococcus peptidase A SPP

External Links
UniProt P0C0J0
EMBL M86905
L26126
L26127
L26128
L26129
L26130
L26131
L26132
L26133
L26135
L26136
L26137
L26138
L26139
L26140
L26141
L26142
L26143
L26144
L26145
L26147
L26148
L26149
L26150
L26151
L26152
L26153
L26154
L26155
L26156
L26157
L26159
L26160
L26161
L26162
AB030578
PIR A37768
RefSeq WP_002991253.1
PDB 1DKI
1PVJ
2UZJ
PDBsum 1DKI
1PVJ
2UZJ
ProteinModelPortal P0C0J0
SMR P0C0J0
ChEMBL CHEMBL2034806
BRENDA 3.4.22.10
SABIO-RK P0C0J0
EvolutionaryTrace P0C0J0
GO GO:0005576
GO:0008234
GO:0009405
GO:0035897
InterPro IPR000200
IPR025896
Pfam PF13734
PF01640
PRINTS PR00797
ProDom PD004169

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0006508

proteolysis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000200

P

Seeded From UniProt

complete

enables

GO:0008234

cysteine-type peptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000200

F

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0843

P

Seeded From UniProt

complete

enables

GO:0008233

peptidase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0645

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0645

P

Seeded From UniProt

complete

enables

GO:0008234

cysteine-type peptidase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0788

F

Seeded From UniProt

complete

enables

GO:0090729

toxin activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0800

F

Seeded From UniProt

complete

GO:0044409

entry into host

PMID:23532847[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Figure 5

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Sumitomo, T et al. (2013) Group A streptococcal cysteine protease cleaves epithelial junctions and contributes to bacterial translocation. J. Biol. Chem. 288 13317-24 PubMed GONUTS page