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STRPY:O85470

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Species (Taxon ID) Streptococcus pyogenes. (1314)
Gene Name(s) sagB (ECO:0000313 with EMBL:AAC25178.1)
Protein Name(s) SagB (ECO:0000313 with EMBL:AAC25178.1)

SagB-type dehydrogenase domain protein (ECO:0000313 with EMBL:AIL10977.1) Streptolysin associated protein SagB (ECO:0000313 with EMBL:AIT77233.1)

External Links
UniProt O85470
EMBL AF067649
CP008926
CP007240
RefSeq WP_010922108.1
STRING 160490.SPy_0739
Proteomes UP000028934
GO GO:0016491
Gene3D 3.40.109.10
InterPro IPR029479
IPR000415
IPR020051
Pfam PF00881
SUPFAM SSF55469
TIGRFAMs TIGR03605

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0009404

toxin metabolic process

PMC101736

ECO:0000315

P

Figure 4: Through directed mutagenesis, the SagB gene was knocked-out and the resulting phenotype observed. In this SBA study, the SagB knockdown resulted in a loss of hemolytic activity, whereas the wild-type would be expected to display this activity through the production of streptolysin S, the process which the gene product of SagB is a part.

Missing: reference

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0016491

P

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000415

F

Seeded From UniProt

complete

Notes

References

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