STRPS:LACA

Species (Taxon ID)	Streptococcus pneumoniae (strain CGSP14). (516950)
Gene Name(s)	lacA (ECO:0000255 with HAMAP-Rule:MF_01555)
Protein Name(s)	Galactose-6-phosphate isomerase subunit LacA (ECO:0000255 with HAMAP-Rule:MF_01555)
External Links
UniProt	B2IPT5
EMBL	CP001033
RefSeq	YP_001835822.1
ProteinModelPortal	B2IPT5
STRING	516950.SPCG_1105
EnsemblBacteria	ACB90357
GeneID	6217984
KEGG	spw:SPCG_1105
PATRIC	19678454
eggNOG	COG0698
HOGENOM	HOG000226301
KO	K01819
OMA	RMITVGA
OrthoDB	EOG6X9MQG
BioCyc	SPNE516950:GI38-1116-MONOMER
UniPathway	UPA00702
Proteomes	UP000001682
GO	GO:0050044 GO:0019388 GO:0005990
Gene3D	3.40.1400.10
HAMAP	MF_01555
InterPro	IPR004783 IPR003500
PANTHER	PTHR30345
Pfam	PF02502
PIRSF	PIRSF005384
SUPFAM	SSF89623
TIGRFAMs	TIGR01118 TIGR00689

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
Contributes to	GO:0050044	galactose-6-phosphate isomerase activity	PMID:20190045	ECO:0000315			F		States that the Streptococcus could not grow after an accumulation of the metabolic intermediates from galactose, particularly the galactose-6-phosphate, with a mutation in the lac genes. Therefore, the isomerase activity is a crucial function for preventing this mode of action.	complete
involved_in	GO:0005975	carbohydrate metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003500 InterPro:IPR036569	P		Seeded From UniProt	complete
involved_in	GO:0005990	lactose catabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004783	P		Seeded From UniProt	complete
enables	GO:0016853	isomerase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003500 InterPro:IPR036569	F		Seeded From UniProt	complete
enables	GO:0050044	galactose-6-phosphate isomerase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004783	F		Seeded From UniProt	complete
enables	GO:0050044	galactose-6-phosphate isomerase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:5.3.1.26	F		Seeded From UniProt	complete
involved_in	GO:0019512	lactose catabolic process via tagatose-6-phosphate	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000001306	P		Seeded From UniProt	complete
enables	GO:0050044	galactose-6-phosphate isomerase activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000001306	F		Seeded From UniProt	complete
involved_in	GO:0005988	lactose metabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0423	P		Seeded From UniProt	complete
enables	GO:0016853	isomerase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0413	F		Seeded From UniProt	complete
involved_in	GO:0019388	galactose catabolic process	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00702	P		Seeded From UniProt	complete
edit table

References

See Help:References for how to manage references in GONUTS.