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STRPF:Q1J7H4

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Species (Taxon ID) Streptococcus pyogenes serotype M4 (strain MGAS10750). (370554)
Gene Name(s) sagG (ECO:0000313 with EMBL:ABF37600.1)
Protein Name(s) Streptolysin S export ATP-binding protein SagG (ECO:0000313 with EMBL:ABF37600.1)
External Links
UniProt Q1J7H4
EMBL CP000262
RefSeq YP_602144.1
ProteinModelPortal Q1J7H4
STRING 370554.MGAS10750_Spy0650
EnsemblBacteria ABF37600
GeneID 4067940
KEGG spi:MGAS10750_Spy0650
PATRIC 19727555
eggNOG COG1131
KO K01990
OMA QSKNVIM
OrthoDB EOG65J54C
BioCyc SPYO370554:GI3S-702-MONOMER
Proteomes UP000002434
GO GO:0005524
GO:0016887
Gene3D 3.40.50.300
InterPro IPR003593
IPR003439
IPR017871
IPR027417
Pfam PF00005
SMART SM00382
SUPFAM SSF52540
PROSITE PS00211
PS50893

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0009404

toxin metabolic process

PMC101736

ECO:0000315

P

Figure 4: This figure details the phenotypic results of an experiment to mutate the SagG gene in S. pyogenes using targeted mutagenesis. The serum bactericidal assay shows a loss of hemolytic activity in the mutant compared to the wild-type activity, evidence of a loss of the production or activity of the streptolysin S toxin. Therefore, the SagG gene product is involved in the metabolism of this toxin.

Missing: reference

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003439
InterPro:IPR017871

F

Seeded From UniProt

complete

enables

GO:0016887

ATPase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003439
InterPro:IPR017871

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000400038

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000400038

F

Seeded From UniProt

complete

Notes

References

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