STRPB:Q1JCM5

Species (Taxon ID)	Streptococcus pyogenes serotype M12 (strain MGAS2096). (370553)
Gene Name(s)	sagI (ECO:0000313 with EMBL:ABF35683.1)
Protein Name(s)	Streptolysin S export transmembrane protein SagI (ECO:0000313 with EMBL:ABF35683.1)
External Links
UniProt	Q1JCM5
EMBL	CP000261
RefSeq	YP_600227.1
ProteinModelPortal	Q1JCM5
STRING	370553.MGAS2096_Spy0631
EnsemblBacteria	ABF35683
GeneID	4066171
KEGG	spj:MGAS2096_Spy0631
PATRIC	19731733
eggNOG	COG0842
HOGENOM	HOG000235476
KO	K01992
OMA	AINTTPR
OrthoDB	EOG6KQ6KC
BioCyc	SPYO370553:GH2N-684-MONOMER
Proteomes	UP000002435
GO	GO:0016021 GO:0005524 GO:0042626
InterPro	IPR000412
PROSITE	PS51012

Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes	Status
	GO:0009404	toxin metabolic process	PMC101736	IMP: Inferred from Mutant Phenotype		P	Figure 4: This figure details the phenotypic results of the knock-out mutagenesis of the SagI gene in S. pyogenes. There is a distinct loss of hemolytic activity in the mutant relative to the wild-type, indicative of a loss of toxin production, the toxin streptolysin S. Therefore, the gene product of SagI is involved in the biosynthesis of the SLS toxin.	Missing: reference
	GO:0005524	ATP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000412	F		complete
	GO:0006810	transport	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000412	P		complete
	GO:0016020	membrane	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000412	C		complete
	GO:0016020	membrane	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013525	C		complete
	GO:0016021	integral to membrane	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0812	C		complete
	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000412	F		complete
	GO:0005524	ATP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000412	F	Seeded From UniProt	complete
	GO:0006810	transport	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000412	P	Seeded From UniProt	complete
	GO:0016020	membrane	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000412	C	Seeded From UniProt	complete
	GO:0016021	integral component of membrane	GO_REF:0000038	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0812	C	Seeded From UniProt	complete
	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000412	F	Seeded From UniProt	complete
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References

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