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STRP2:A0A0H2ZQ65
Contents
| Species (Taxon ID) | Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466). (373153) | |
| Gene Name(s) | ccpA (ECO:0000313 with EMBL:ABJ55405.1) | |
| Protein Name(s) | Catabolite control protein A (ECO:0000313 with EMBL:ABJ55405.1) | |
| External Links | ||
| UniProt | A0A0H2ZQ65 | |
| EMBL | CP000410 | |
| RefSeq | WP_000990602.1 | |
| ProteinModelPortal | A0A0H2ZQ65 | |
| EnsemblBacteria | ABJ55405 | |
| KEGG | spd:SPD_1797 | |
| KO | K02529 | |
| OMA | HKSTIER | |
| Proteomes | UP000001452 | |
| CollecTF | EXPREG_000000e0 | |
| GO | GO:0003677 GO:0006355 GO:0006351 | |
| CDD | cd01392 | |
| Gene3D | 1.10.260.40 | |
| InterPro | IPR006377 IPR000843 IPR010982 IPR028082 | |
| Pfam | PF00356 | |
| PRINTS | PR00036 | |
| SMART | SM00354 | |
| SUPFAM | SSF47413 SSF53822 | |
| TIGRFAMs | TIGR01481 | |
| PROSITE | PS50932 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0010944 |
negative regulation of transcription by competitive promoter binding |
ECO:0000315 |
P |
Figure 4A: Which describes the negative regulation of B-galactosidase via the ccpa protein in Streptococcus pneumoniae strain D39 serotype 2. In the control, the deletion of catabolite control protein A (ccpa) resulted in an increase in the transcript levels of bga and pts. In the the BgaAC mutant, a decrease in transcription occurred for both bga and pts. Figure 5: Showing that the D39 pts promoter expressed a higher affinity for the CcpA protein rather than the second repressor. The BgaAC mutant bacteria with its pts promoter expressed the higher affinity for the second repressor. |
complete | |||||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Kaufman, GE & Yother, J (2007) CcpA-dependent and -independent control of beta-galactosidase expression in Streptococcus pneumoniae occurs via regulation of an upstream phosphotransferase system-encoding operon. J. Bacteriol. 189 5183-92 PubMed GONUTS page
