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STRP1:PILIN

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Species (Taxon ID) Streptococcus pyogenes serotype M1. (301447)
Gene Name(s) No Information Provided.
Protein Name(s) Pilin

Lancefield T antigen Pilus backbone structural protein

External Links
UniProt Q9A1S2
EMBL AE004092
CP000017
RefSeq NP_268517.1
YP_281473.1
PDB 3B2M
3GLD
3GLE
PDBsum 3B2M
3GLD
3GLE
ProteinModelPortal Q9A1S2
SMR Q9A1S2
STRING 160490.SPy_0128
EnsemblBacteria AAK33238
AAZ50728
GeneID 3572810
900460
KEGG spy:SPy_0128
spz:M5005_Spy_0109
PATRIC 19714069
eggNOG NOG12793
HOGENOM HOG000235125
OMA WTVDVYV
OrthoDB EOG62K1WZ
BioCyc SPYO160490:GJ81-138-MONOMER
SPYO293653:GHFC-159-MONOMER
EvolutionaryTrace Q9A1S2
Proteomes UP000000750
UP000002702
GO GO:0005618
GO:0005576
GO:0009289
InterPro IPR017503
IPR022464
Pfam PF12892
TIGRFAMs TIGR03065
TIGR03786

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0043709

cell adhesion involved in single-species biofilm formation

PMID:17501921[1]

ECO:0000315

P

Figure 10. Biofilm formation by GAS SF370 wild type (WT), pilus knockout mutants and complemented strains. GAS deletion mutants show smaller biofilm formation

complete

GO:0034113

heterotypic cell-cell adhesion

PMID:17501921[1]

ECO:0000314

P

Figure 12. Reactivity of human patient sera with GAS pili. FCT protein binding to protein microarray show 80% of infected patients bound the FCT pili protein.

complete

GO:0009418

pilus shaft

PMID:18063798[2]

ECO:0000315

C

Figure S1. MS/MS spectrum of the peptide with mass-to-charge ratio (m/z) 552.32+ generated from trypsin/AspN double-digest of Spy0128. Mutation of Spy0128 gene leads to degradation of previously protected residues by trypsin

complete

GO:0009289

pilus

PMID:17501921[1]

ECO:0000315

C

Figure 1. Expression of M1 pili in GAS SF370 and mutant derivatives. Deletion mutants failed to produce pili as shown by immunoelectron microscopy

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

part_of

GO:0009289

pilus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0281
UniProtKB-SubCell:SL-0113

C

Seeded From UniProt

complete

part_of

GO:0005618

cell wall

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0134
UniProtKB-SubCell:SL-0041

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Manetti, AG et al. (2007) Streptococcus pyogenes pili promote pharyngeal cell adhesion and biofilm formation. Mol. Microbiol. 64 968-83 PubMed GONUTS page
  2. Kang, HJ et al. (2007) Stabilizing isopeptide bonds revealed in gram-positive bacterial pilus structure. Science 318 1625-8 PubMed GONUTS page